Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular Location (Q36694583)

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scientific article published on August 1, 1993

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English	Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular Location	scientific article published on August 1, 1993

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scholarly article

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15 August 2017

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular Location (English)

1 reference

10.1128/MCB.13.8.4760-4769.1993

https://api.crossref.org/works/10.1128/MCB.13.8.4760-4769.1993

19 August 2024

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R. J. Bram

1

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19 August 2024

D. T. Hung

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

P. K. Martin

3

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19 August 2024

S. L. Schreiber

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

G. R. Crabtree

5

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19 August 2024

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publication date

1 August 1993

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15 August 2017

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https://europepmc.org/articles/pmc360102?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

http://mcb.asm.org/cgi/content/abstract/13/8/4760

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7687744/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7687744/?tool=EBI

online access status

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

https://europepmc.org/articles/PMC360102

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

https://europepmc.org/articles/PMC360102?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7687744

19 August 2024

https://journals.asm.org/doi/pdf/10.1128/mcb.13.8.4760-4769.1993

1 reference

10.1128/MCB.13.8.4760-4769.1993

https://api.crossref.org/works/10.1128/MCB.13.8.4760-4769.1993

19 August 2024

https://www.tandfonline.com/doi/pdf/10.1128/mcb.13.8.4760-4769.1993

1 reference

10.1128/MCB.13.8.4760-4769.1993

https://api.crossref.org/works/10.1128/MCB.13.8.4760-4769.1993

19 August 2024

Molecular and Cellular Biology

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Europe PubMed Central

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15 August 2017

13

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Europe PubMed Central

PMC publication ID

15 August 2017

8

1 reference

Europe PubMed Central

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15 August 2017

4760-4769

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Identification of the NH2-terminal blocking group of calcineurin B as myristic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Activation of calcineurin by limited proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Cyclophilin, a primary molecular target for cyclosporine. Structural and functional implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Calcium-dependent association of a protein complex with the lymphocyte plasma membrane: probable identity with calmodulin-calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Molecular cloning of murine p68, a Ca2+-binding protein of the lipocortin family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

An endoplasmic reticulum-specific cyclophilin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Epitope tagging and protein surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Molecular cloning and overexpression of the human FK506-binding protein FKBP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

The mechanism of action of cyclosporin A and FK506

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Do we know the site of action of cyclosporin?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Biological effects of cyclosporin A: A new antilymphocytic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

30 September 2017

Jun family members are controlled by a calcium-regulated, cyclosporin A-sensitive signaling pathway in activated T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

28 June 2018

Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

28 June 2018

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

28 June 2018

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

28 June 2018

A rapamycin-selective 25-kDa immunophilin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=360102

28 June 2018

Effect of cyclosporin A on lymphocyte activation by the calcium ionophore A23187

1 reference

https://pubmed.ncbi.nlm.nih.gov/7687744

12 December 2020

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Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7687744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional domain structure of calcineurin A: mapping by limited proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7687744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7687744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hetero-homogeneous processes involved in oxidative conversion of methane, ethane and hydrocarbon mixtures over basic oxides

11

1 reference

10.1128/MCB.13.8.4760-4769.1993

https://api.crossref.org/works/10.1128/MCB.13.8.4760-4769.1993

19 August 2024

Identifiers

10.1128/MCB.13.8.4760

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

10.1128/MCB.13.8.4760-4769.1993

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7687744

19 August 2024

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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