IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. (Q36742236)

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scientific article published on 23 June 2008

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English	IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.	scientific article published on 23 June 2008

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9 January 2020

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition (English)

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9 January 2020

Benjamin M. Segal

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9 January 2020

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Mark A Kroenke

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9 January 2020

Thaddeus J Carlson

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9 January 2020

Anuska V Andjelkovic

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9 January 2020

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23 June 2008

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9 January 2020

Journal of Experimental Medicine

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9 January 2020

205

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9 January 2020

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9 January 2020

1535-1541

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9 January 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2442630/fullTextXML

based on heuristic

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The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

1 reference

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The spectrum of neuromyelitis optica

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

1 reference

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1 reference

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29 September 2017

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

29 September 2017

T-cell properties determine disease site, clinical presentation, and cellular pathology of experimental autoimmune encephalomyelitis

1 reference

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29 September 2017

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

29 September 2017

Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease

1 reference

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

1 reference

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29 September 2017

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

29 September 2017

TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease

1 reference

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29 September 2017

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

1 reference

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29 September 2017

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

29 September 2017

Immune cell populations in cutaneous delayed-type hypersensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

29 September 2017

Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice

1 reference

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29 September 2017

Increased release of interleukin-12p40 in MS: association with intracerebral inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

28 June 2018

Interleukin-17.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

28 June 2018

Interferon gamma responses to myelin peptides in multiple sclerosis correlate with a new clinical measure of disease progression

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

5 September 2018

Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

5 September 2018

Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

5 September 2018

Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

5 September 2018

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442630

5 September 2018

IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with anti-granulocyte antibodies inhibits the effector phase of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 driven upregulation of P-selectin ligand on myelin-specific T cells is a critical step in an animal model of autoimmune demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

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Autoimmune Uveitis Elicited with Antigen-Pulsed Dendritic Cells Has a Distinct Clinical Signature and Is Driven by Unique Effector Mechanisms: Initial Encounter with Autoantigen Defines Disease Phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18573909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20080159

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Europe PubMed Central

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9 January 2020

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Europe PubMed Central

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9 January 2020

PubMed publication ID

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Europe PubMed Central

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9 January 2020

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