Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines. (Q36787548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18519811%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines (English)

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8 January 2020

6

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8 January 2020

author name string

Michael A Morse

1

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8 January 2020

Amy C Hobeika

2

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8 January 2020

Takuya Osada

3

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8 January 2020

Delila Serra

4

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8 January 2020

Donna Niedzwiecki

5

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8 January 2020

Timothy M Clay

7

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8 January 2020

language of work or name

English

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publication date

2 June 2008

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8 January 2020

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8 January 2020

volume

112

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8 January 2020

issue

3

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8 January 2020

page(s)

610-618

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IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity

8 January 2020

cites work

1 reference

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The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

29 September 2017

1 reference

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Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer

29 September 2017

1 reference

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IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice

29 September 2017

1 reference

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Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

29 September 2017

1 reference

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Regulatory T cells in ovarian cancer: biology and therapeutic potential

29 September 2017

1 reference

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Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

29 September 2017

1 reference

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In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

29 September 2017

1 reference

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

29 September 2017

1 reference

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Escape from immunotherapy: possible mechanisms that influence tumor regression/progression.

29 September 2017

1 reference

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Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Immunoregulatory T cells in tumor immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination.

29 September 2017

1 reference

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Increase of regulatory T cells in the peripheral blood of cancer patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

CD4+ CD25+ suppressor T cells: more questions than answers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Pivotal phase III trial of two dose levels of denileukin diftitox for the treatment of cutaneous T-cell lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481547

Interleukin 2 receptor-targeted cytotoxicity. Receptor binding requirements for entry of a diphtheria toxin-related interleukin 2 fusion protein into cells.

29 September 2017

1 reference

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Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis.

27 June 2018

1 reference

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Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation

5 September 2018

1 reference

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CD4+CD25+ regulatory T cells that secrete TGFbeta and IL-10 are preferentially induced by a vaccine vector

20 October 2018

1 reference

12 December 2020

Phase I study of immunization with dendritic cells modified with fowlpox encoding carcinoembryonic antigen and costimulatory molecules

1 reference

12 December 2020

Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro

1 reference

12 December 2020

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

1 reference

12 December 2020

10.1182/BLOOD-2008-01-135319

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18519811%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18519811%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

18519811

1 reference