Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions (Q36897400)

16 August 2017

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title

Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions (English)

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16 August 2017

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Vladimir Y Toshchakov

series ordinal

1

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16 August 2017

Stefanie N Vogel

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

1 July 2007

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Expert Opinion on Biological Therapy

16 August 2017

published in

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16 August 2017

volume

7

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16 August 2017

issue

7

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16 August 2017

page(s)

1035-1050

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Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease

16 August 2017

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The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

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A novel inhibitory peptide of Toll-like receptor signaling limits lipopolysaccharide-induced production of inflammatory mediators and enhances survival in mice

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain. turtle nija occasionally

21 January 2018

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Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling

21 January 2018

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21 January 2018

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Toll-like receptors as molecular switches

21 January 2018

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

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Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation

21 January 2018

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21 January 2018

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Binding specificity of Toll-like receptor cytoplasmic domains

21 January 2018

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MyD88, an adapter protein involved in interleukin-1 signaling

21 January 2018

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Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase

21 January 2018

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

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Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

21 January 2018

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21 January 2018

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21 January 2018

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Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

21 January 2018

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Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways

21 January 2018

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Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling

21 January 2018

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An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2

21 January 2018

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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

21 January 2018

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

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Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets

21 January 2018

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Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor

21 January 2018

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Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

21 January 2018

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58)

21 January 2018

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Developing novel hCT derived cell-penetrating peptides with improved metabolic stability

21 January 2018

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A D-amino acid peptide inhibitor of NF-kappa B nuclear localization is efficacious in models of inflammatory disease

21 January 2018

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Complementarity of Structure Ensembles in Protein-Protein Binding

21 January 2018

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10.1517/14712598.7.7.1035

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference