Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. (Q36920080)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802435%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802435%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

0 references

1 reference

2

1 reference

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14 January 2020

author name string

Michael D Horwich

series ordinal

1

1 reference

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14 January 2020

publication date

1 January 2008

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14 January 2020

1 reference

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14 January 2020

volume

3

1 reference

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14 January 2020

issue

10

1 reference

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14 January 2020

page(s)

1537-1549

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LNA-mediated microRNA silencing in non-human primates

14 January 2020

cites work

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Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

29 September 2017

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Inhibition of microRNA with antisense oligonucleotides

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Most Caenorhabditis elegans microRNAs are individually not essential for development or viability

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

29 September 2017

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

29 September 2017

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Molecular basis for target RNA recognition and cleavage by human RISC.

29 September 2017

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29 September 2017

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The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

29 September 2017

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29 September 2017

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MicroRNA expression profiles for the NCI-60 cancer cell panel

29 September 2017

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Requirement of bic/microRNA-155 for normal immune function

29 September 2017

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Specificity, duplex degradation and subcellular localization of antagomirs

29 September 2017

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The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

29 September 2017

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Double-stranded regions are essential design components of potent inhibitors of RISC function

29 September 2017

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Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2

29 September 2017

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Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

29 September 2017

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Characterization of microRNA expression levels and their biological correlates in human cancer cell lines

29 September 2017

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Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

29 September 2017

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29 September 2017

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29 September 2017

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A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

29 September 2017

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Systematic identification of microRNA functions by combining target prediction and expression profiling

29 September 2017

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The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

29 September 2017

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miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

29 September 2017

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29 September 2017

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Silencing of microRNAs in vivo with 'antagomirs'

29 September 2017

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Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth

29 September 2017

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Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

29 September 2017

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The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans

29 September 2017

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

29 September 2017

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microRNA target predictions across seven Drosophila species and comparison to mammalian targets

29 September 2017

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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

29 September 2017

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Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development

29 September 2017

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Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

29 September 2017

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A microRNA polycistron as a potential human oncogene

29 September 2017

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

29 September 2017

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A cellular microRNA mediates antiviral defense in human cells

29 September 2017

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29 September 2017

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MicroRNAs regulate brain morphogenesis in zebrafish

29 September 2017

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29 September 2017

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Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation

29 September 2017

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

29 September 2017

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

29 September 2017

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

29 September 2017

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Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

29 September 2017

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A pancreatic islet-specific microRNA regulates insulin secretion

29 September 2017

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MicroRNA-143 regulates adipocyte differentiation

29 September 2017

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Kinetic analysis of the RNAi enzyme complex

29 September 2017

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Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

29 September 2017

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MicroRNA-directed cleavage of HOXB8 mRNA

29 September 2017

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Sequence-specific inhibition of small RNA function

29 September 2017

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Specificity of microRNA target selection in translational repression

29 September 2017

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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

29 September 2017

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Prediction of mammalian microRNA targets

29 September 2017

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MicroRNAs modulate hematopoietic lineage differentiation

29 September 2017

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Asymmetry in the assembly of the RNAi enzyme complex

29 September 2017

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The nuclear RNase III Drosha initiates microRNA processing

29 September 2017

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Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes

29 September 2017

1 reference

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The small RNA profile during Drosophila melanogaster development

29 September 2017

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Mfold web server for nucleic acid folding and hybridization prediction

29 September 2017

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siRNAs can function as miRNAs

29 September 2017

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Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets

29 September 2017

1 reference

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A microRNA in a multiple-turnover RNAi enzyme complex

29 September 2017

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Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

29 September 2017

1 reference

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

29 September 2017

1 reference

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Identification of novel genes coding for small expressed RNAs

29 September 2017

1 reference

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

29 September 2017

1 reference

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Role for a bidentate ribonuclease in the initiation step of RNA interference

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding

29 September 2017

1 reference

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Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Production of homozygous mutant ES cells with a single targeting construct

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Diversity of microRNAs in human and chimpanzee brain

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

LNA-modified oligonucleotides mediate specific inhibition of microRNA function.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Stem cell division is regulated by the microRNA pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Inhibition of micro-RNA-induced RNA silencing by 2'-o-methyl oligonucleotides in Drosophila S2 cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Computational identification of microRNA targets.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2559958

RNAi-Mediated Allelic trans-Interaction at the Imprinted Rtl1/Peg11 Locus

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPROT.2008.145

Gene targeting by homologous recombination in Drosophila

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPROT.2008.145

31 March 2020

Identifiers

DOI

10.1038/NPROT.2008.145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802435%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802435%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18802435

1 reference