G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis. (Q36976015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

9 January 2020

main subject

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

David C New

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kelvin Wu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Alice W S Kwok

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

19 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

6025-6036

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949438%20AND%20SRC:MED&resulttype=core&format=json

Physiological roles of PKB/Akt isoforms in development and disease

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

PI 3-kinase, Akt and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Protein kinase B/Akt at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The Sequence of the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Drug discovery: a historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

G protein-coupled receptors in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Heterotrimeric G-protein betagamma-dimers in growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Phosphoinositide 3-kinase signalling--which way to target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Receptor tyrosine kinases are signaling intermediates of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Src family kinases, key regulators of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Stromal cell-derived factor-1alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The Akt-GSK-3 signaling cascade in the actions of dopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Arrestins block G protein-coupled receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Constitutively active alpha subunits of G(q/11) and G(12/13) families inhibit activation of the pro-survival Akt signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Involvement of G i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC-12 cells and cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Mutant G-protein-coupled receptors as a cause of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Receptor isoforms mediate opposing proliferative effects through gbetagamma-activated p38 or Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Lipoxins inhibit Akt/PKB activation and cell cycle progression in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Activation of muscarinic M4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

cAMP signaling selectively influences Ras effectors pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Caspase function in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

NFkappaB-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Urinary pheromones promote ERK/Akt phosphorylation, regeneration and survival of vomeronasal (V2R) neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Lysophosphatidic acid as a novel cell survival/apoptotic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Role of the CC chemokine receptor 9/TECK interaction in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

EGFR signal transactivation in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Lysophosphatidic acid promotes survival of androgen-insensitive prostate cancer PC3 cells via activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X

Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06116.X