Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells (Q37011852)

17 August 2017

Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells (English)

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17 August 2017

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Akari Inada

1

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17 August 2017

Yoshiyuki Hamamoto

2

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17 August 2017

Yoshiyuki Tsuura

3

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17 August 2017

Jun-ichi Miyazaki

4

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17 August 2017

Shinya Toyokuni

5

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17 August 2017

Yu Ihara

6

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17 August 2017

Koichiro Nagai

7

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17 August 2017

Yuichiro Yamada

8

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17 August 2017

Susan Bonner-Weir

9

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17 August 2017

Yutaka Seino

10

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17 August 2017

language of work or name

English

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publication date

1 April 2004

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Molecular and Cellular Biology

17 August 2017

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17 August 2017

24

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17 August 2017

7

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17 August 2017

2831-2841

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describes a project that uses

17 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC371116/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

29 September 2017

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Cyclin A in cell cycle control and cancer

29 September 2017

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Regulation of insulin gene transcription

29 September 2017

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Activating transcription factor 1 and CREB are important for cell survival during early mouse development

29 September 2017

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Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

29 September 2017

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Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells

29 September 2017

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Transcriptional regulation by cyclic AMP-responsive factors

29 September 2017

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The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID

29 September 2017

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Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver.

29 September 2017

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Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

29 September 2017

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Cyclic AMP signaling and gene regulation

29 September 2017

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Differential regulation and transcriptional control of immediate early gene expression in forskolin-treated WEHI7.2 thymoma cells

29 September 2017

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Activation of the rat cyclin A promoter by ATF2 and Jun family members and its suppression by ATF4.

29 September 2017

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A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos

29 September 2017

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Transcriptional control of circadian hormone synthesis via the CREM feedback loop

29 September 2017

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cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes

29 September 2017

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Nutrient regulation of insulin gene expression.

29 September 2017

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Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

29 September 2017

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Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM.

29 September 2017

1 reference

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Overexpression of human cyclin A advances entry into S phase.

29 September 2017

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Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex

29 September 2017

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Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

29 September 2017

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Somatostatin gene expression in pancreatic islet cells is directed by cell-specific DNA control elements and DNA-binding proteins

29 September 2017

1 reference

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Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain

29 September 2017

1 reference

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A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

29 September 2017

1 reference

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Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers

29 September 2017

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Structure and function of the protein CRE-BP1: heterogeneity of the protein that binds to the cAMP-responsive element

29 September 2017

1 reference

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Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells

29 September 2017

1 reference

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CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

29 September 2017

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c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins

29 September 2017

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Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

29 September 2017

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1992 R.D. Lawrence Lecture. The regulation of insulin gene expression

29 September 2017

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Cyclic adenosine monophosphate prevents the glucocorticoid-mediated inhibition of insulin gene expression in rodent islet cells

29 September 2017

1 reference

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c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements

29 September 2017

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Distinct properties of the cAMP-responsive element of the rat insulin I gene.

29 September 2017

1 reference

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Cyclic AMP signalling and cellular proliferation: regulation of CREB and CREM.

29 September 2017

1 reference

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The beta cell transcription factors and development of the pancreas

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

The insulin gene promoter. A simplified nomenclature

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Positive and negative regulation of the human insulin gene by multiple trans-acting factors

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Functional characterization of a cAMP-responsive element of the rat insulin I gene

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Control of insulin gene expression by glucose

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Cell cycle promoting activity of JunB through cyclin A activation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

4 September 2018

Cyclic AMP signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371116

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA

4 September 2018

1 reference

12 December 2020

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

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12 December 2020

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

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12 December 2020

Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats

1 reference

12 December 2020

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

1 reference

12 December 2020

Functional analysis of the mouse ICER (Inducible cAMP Early Repressor) promoter: evidence for a protein that blocks calcium responsiveness of the CAREs (cAMP autoregulatory elements)

1 reference

12 December 2020

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1 reference

12 December 2020

10.1128/MCB.24.7.2831-2841.2004

Identifiers

DOI

1 reference

17 August 2017

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17 August 2017

PubMed publication ID

15024072

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