Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update (Q37043914)

17 August 2017

1 reference

title

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update (English)

1 reference

17 August 2017

Natalie L Trevaskis

1

1 reference

17 August 2017

William N Charman

series ordinal

2

1 reference

17 August 2017

Christopher J H Porter

series ordinal

3

1 reference

17 August 2017

language of work or name

English

0 references

publication date

7 November 2007

1 reference

Advanced Drug Delivery Reviews

17 August 2017

published in

1 reference

17 August 2017

volume

60

1 reference

17 August 2017

issue

6

1 reference

17 August 2017

page(s)

702-716

1 reference

Origin and characteristics of endogenous lipid in thoracic duct lymph in rat

17 August 2017

cites work

1 reference

12 December 2020

Dietary fat inhibits the intestinal metabolism of the carcinogen benzo[a]pyrene in fish

1 reference

12 December 2020

Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV

1 reference

12 December 2020

Apolipoprotein B synthesis in rat small intestine: regulation by dietary triglyceride and biliary lipid.

1 reference

12 December 2020

1 reference

12 December 2020

Biosynthesis of triacylglycerols

1 reference

12 December 2020

Intestinal lipoprotein metabolism.

1 reference

12 December 2020

The effect of oils on the lymphatic absorption of DDT

1 reference

12 December 2020

VIP21/caveolin is a cholesterol-binding protein

1 reference

12 December 2020

Fatty acid-binding protein and its relation to fatty acid oxidation

1 reference

12 December 2020

Intestinal lipid absorption and transport

1 reference

12 December 2020

Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin

1 reference

12 December 2020

Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

1 reference

12 December 2020

Hepatitis B virus infection in lymphatic tissues in inactive hepatitis B carriers.

1 reference

12 December 2020

Intestinal lymphatic drug transport: an update

1 reference

12 December 2020

The origin of cholesterol in the mesenteric lymph of the rat

1 reference

12 December 2020

Factors influencing triacylglycerol delivery into mesenteric lymph

1 reference

12 December 2020

ESTIMATION AND SUBCELLULAR DISTRIBUTION OF LECITHINASE ACTIVITY IN RAT INTESTINAL MUCOSA

1 reference

12 December 2020

Sterol carrier protein-2: not just for cholesterol any more

1 reference

12 December 2020

1,3-dipalmitoylglycerol ester of chlorambucil as a lymphotropic, orally administrable antineoplastic agent

1 reference

12 December 2020

Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability

1 reference

12 December 2020

Biosynthesis of chylomicron triacylglycerols by rats fed glyceryl or alkyl esters of menhaden oil fatty acids

1 reference

12 December 2020

Evidence for separate pathways of chylomicron and very low-density lipoprotein assembly and transport by rat small intestine

1 reference

12 December 2020

1 reference

12 December 2020

Mechanisms of digestion and absorption of dietary vitamin A.

1 reference

12 December 2020

Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat.

1 reference

12 December 2020

Cholesteryl ester absorption by small intestinal brush border membrane is protein-mediated

1 reference

12 December 2020

Contribution of lymphatically transported testosterone undecanoate to the systemic exposure of testosterone after oral administration of two andriol formulations in conscious lymph duct-cannulated dogs.

1 reference

12 December 2020

The portal transport of absorbed fatty acids

1 reference

12 December 2020

Incorporation of Dietary Lecithin and Lysolecithin into Lymph Chylomicrons in the Rat

1 reference

12 December 2020

Human ABC transporter ABCG2 in xenobiotic protection and redox biology

1 reference

12 December 2020

Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice.

1 reference

12 December 2020

Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols

1 reference

12 December 2020

Lipid vehicles for intestinal lymphatic drug absorption

1 reference

12 December 2020

[Lymphatic delivery of drugs and its application to cancer chemotherapy (author's transl)]

1 reference

12 December 2020

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

1 reference

12 December 2020

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability

1 reference

12 December 2020

New insights in the lymphatic spread of oesophageal cancer and its implications for the extent of surgical resection

1 reference

12 December 2020

The structure of lymphatic capillaries in lymph formation

1 reference

12 December 2020

Oral testosterone, a reappraisal

1 reference

12 December 2020

Comparative analyses of canine distemper viral isolates from clinical cases of canine distemper in vaccinated dogs

1 reference

12 December 2020

The role of the lymphatic transport in the enteral absorption of naftifine by the rat

1 reference

12 December 2020

Monoacylglycerol metabolism in human intestinal Caco-2 cells: evidence for metabolic compartmentation and hydrolysis

1 reference

12 December 2020

CD36 is a receptor for oxidized low density lipoprotein

1 reference

12 December 2020

Sterol carrier protein-2

1 reference

12 December 2020

Intestinal lymphatic absorption of cyclosporin A following oral administration in an olive oil solution in rats

1 reference

12 December 2020

Role of ABCG1 and other ABCG family members in lipid metabolism

1 reference

12 December 2020

Pentadecanoic acid-5-C14; its absorption and lymphatic transport

1 reference

12 December 2020

Lipid-based formulations for intestinal lymphatic delivery

1 reference

12 December 2020

Effect of Pluronic L81, a hydrophobic surfactant, on intestinal mucosal cholesterol homeostasis

1 reference

12 December 2020

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

1 reference

12 December 2020

Identification of a receptor mediating absorption of dietary cholesterol in the intestine

1 reference

12 December 2020

Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function

1 reference

12 December 2020

The entry of foreign compounds into the thoracic duct lymph of the rat.

1 reference

12 December 2020

Localization and regulation of the putative membrane fatty-acid transporter (FAT) in the small intestine. Comparison with fatty acid-binding proteins (FABP)

1 reference

12 December 2020

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

1 reference

12 December 2020

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

1 reference

12 December 2020

Intestinal absorption of lecithin and lysolecithin by lymph fistula rats

1 reference

12 December 2020

Different impacts of intestinal lymphatic transport on the oral bioavailability of structurally similar synthetic lipophilic cannabinoids: dexanabinol and PRS-211,220

1 reference

12 December 2020

Uptake and metabolism of circulating fatty acids by rat intestine

1 reference

12 December 2020

Nuclear receptors and lipid physiology: opening the X-files

1 reference

12 December 2020

Accelerated lipid absorption in mice overexpressing intestinal SR-BI.

1 reference

12 December 2020

Lipoproteins associated with the Golgi apparatus isolated from epithelial cells of rat small intestine

1 reference

12 December 2020

Bile increases intestinal lymphatic drug transport in the fasted rat.

1 reference

12 December 2020

Liver Fatty Acid-binding Protein Initiates Budding of Pre-chylomicron Transport Vesicles from Intestinal Endoplasmic Reticulum

1 reference

12 December 2020

Hydrocarbon transport in chylomicrons and high‐density lipoproteins in rat

1 reference

12 December 2020

Fatty acid binding protein in locust and mammalian muscle. Comparison of structure, function and regulation

1 reference

12 December 2020

Intestinal cholesterol transport proteins: an update and beyond

1 reference

12 December 2020

Effect of increasing lipid loads on the ability of the endoplasmic reticulum to transport lipid to the Golgi

1 reference

12 December 2020

Successful in silico predicting of intestinal lymphatic transfer

1 reference

12 December 2020

Uptake of fatty acids by jejunal mucosal cells is mediated by a fatty acid binding membrane protein

1 reference

12 December 2020

ABC transporters in lipid transport

1 reference

12 December 2020

The effects of pluronics block copolymers and Cremophor EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cells

1 reference

12 December 2020

Lymph flow pattern in the intact thoracic duct in sheep.

1 reference

12 December 2020

Isolation and characterization of a mucosal triacylglycerol pool undergoing hydrolysis

1 reference

12 December 2020

Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor

1 reference

12 December 2020

Receptor (SLAM [CD150]) recognition and the V protein sustain swift lymphocyte-based invasion of mucosal tissue and lymphatic organs by a morbillivirus

1 reference

12 December 2020

Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems

1 reference

12 December 2020

Stimulation of Triglyceride-Rich Lipoprotein Secretion by Polysorbate 80: In Vitro and in Vivo Correlation Using Caco-2 Cells and a Cannulated Rat Intestinal Lymphatic Model

1 reference

12 December 2020

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

1 reference

12 December 2020

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

1 reference

12 December 2020

Role of lymphoid organs in the pathogenesis of human immunodeficiency virus (HIV) infection

1 reference

12 December 2020

Intracellular lipid binding proteins of the small intestine

1 reference

12 December 2020

Important effect of food on the bioavailability of oral testosterone undecanoate

1 reference

12 December 2020

Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid

1 reference

12 December 2020

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

1 reference

12 December 2020

Intestinal lipoprotein synthesis and secretion

1 reference

12 December 2020

Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane

1 reference

12 December 2020

Phosphatidylcholine inhibits and lysophosphatidylcholine enhances the lymphatic absorption of alpha-tocopherol in adult rats

1 reference

12 December 2020

Intestinal lymph as pathway for transport of absorbed fatty acids of different chain lengths

1 reference

12 December 2020

Acyl-CoA oxidase activity and peroxisomal fatty acid oxidation in rat tissues.

1 reference

12 December 2020

A dual, concentration-dependent absorption mechanism of linoleic acid by rat jejunum in vitro

1 reference

12 December 2020

Role of pancreatic cholesterol esterase in the uptake and esterification of cholesterol by isolated intestinal cells

1 reference

12 December 2020

Portal transport of absorbed lipids in rats

1 reference

12 December 2020

Absorption of a pharmacological dose of vitamin D3 from two different lipid vehicles in man: comparison of peanut oil and a medium chain triglyceride

1 reference

12 December 2020

Animal models for the study of intestinal lymphatic drug transport

1 reference

12 December 2020

Portal transport of long acyl chain lipids: effect of phosphatidylcholine and low infusion rates

1 reference

12 December 2020

Uptake of micellar long-chain fatty acid and sn-2-monoacylglycerol into human intestinal Caco-2 cells exhibits characteristics of protein-mediated transport

1 reference

12 December 2020

Interactions between microsomal triglyceride transfer protein and apolipoprotein B within the endoplasmic reticulum in a heterologous expression system.

1 reference

12 December 2020

Fatty acid regulation of fatty acid-binding protein expression in the small intestine

1 reference

12 December 2020

Steady-state kinetic analysis of triacylglycerol delivery into mesenteric lymph

1 reference

12 December 2020

The lymphatic route. 1) Albumin and hyaluronidase modify the normal distribution of interferon in lymph and plasma

1 reference

12 December 2020

Long-chain fatty acid uptake into adipocytes depends on lipid raft function

1 reference

12 December 2020

Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs

1 reference

12 December 2020

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

12 December 2020

Effect of oily vehicles on absorption of mepitiostane by the lymphatic system in rats

1 reference

12 December 2020

The pharmacology and metabolism of testosterone undecanoate (TU), a new orally active androgen

1 reference

12 December 2020

Recombinant lipoproteins: implications for structure and assembly of native lipoproteins

1 reference

12 December 2020

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

1 reference

12 December 2020

Microsomal triglyceride transfer protein: a multifunctional protein

1 reference

12 December 2020

Common mechanisms of monoacylglycerol and fatty acid uptake by human intestinal Caco-2 cells

1 reference

12 December 2020

ROLE OF BILE AND PANCREATIC JUICE IN CHOLESTEROL ABSORPTION AND ESTERIFICATION

1 reference

12 December 2020

Electron microscopic study of intestinal fat absorption in vitro from mixed micelles containing linolenic acid, monoolein, and bile salt

1 reference

12 December 2020

Formation and transport of chylomicrons by enterocytes to the lymphatics

1 reference

12 December 2020

Comparison of total oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats

1 reference

12 December 2020

The metastatic cascade in prostate cancer

1 reference

12 December 2020

Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats

1 reference

12 December 2020

Effect of bile on absorption of mepitiostane by the lymphatic system in rats

1 reference

12 December 2020

Role of the intestine in chylomicron remnant clearance

1 reference

12 December 2020

Chylomicron assembly and catabolism: role of apolipoproteins and receptors.

1 reference

12 December 2020

The PPARs: from orphan receptors to drug discovery

1 reference

12 December 2020

Uptake of long-chain fatty acids in HepG2 cells involves caveolae: analysis of a novel pathway.

1 reference

12 December 2020

Intestinal triacylglycerol storage pool size changes under differing physiological conditions

1 reference

12 December 2020

Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine

1 reference

12 December 2020

Dietary saturated fatty acid content affects lymph lipoproteins: studies in the rat

1 reference

12 December 2020

Bioavailability of oral testosterone in males

1 reference

12 December 2020

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

1 reference

12 December 2020

The importance of the lysophosphatidylcholine and choline moiety of bile phosphatidylcholine in lymphatic transport of fat

1 reference

12 December 2020

Caco-2 cells as a model for intestinal lipoprotein synthesis and secretion.

1 reference

12 December 2020

A comparison of absorption of glycerol tristearate and glycerol trioleate by rat small intestine

1 reference

12 December 2020

Intestinal absorption of polyunsaturated phosphatidylcholine in the rat

1 reference

12 December 2020

A re-examination of the fate of glyceride-glycerol in neutral lipid absorption and transport

1 reference

12 December 2020

Very low density lipoproteins in intestinal lymph: origin, composition, and role in lipid transport in the fasting state

1 reference

12 December 2020

Electron microscopic studies of the assembly, intracellular transport, and secretion of chylomicrons by rat intestine

1 reference

12 December 2020

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

1 reference

12 December 2020

Protein-mediated transfer of fluorescent-labeled phospholipids across brush border of rabbit intestine

1 reference

12 December 2020

The effect of different oils on the absorption of probucol in the rat

1 reference

12 December 2020

The interaction of lipophilic drugs with intestinal fatty acid-binding protein.

1 reference

12 December 2020

Transport of proteins across the endoplasmic reticulum membrane

1 reference

12 December 2020

An examination of the factors affecting intestinal lymphatic transport of dietary lipids

1 reference

12 December 2020

The role of the lymphatic system in subcutaneous absorption of macromolecules in the rat model

1 reference

12 December 2020

Role of Biliary Lecithin in Lymphatic Transport of Fat

1 reference

12 December 2020

Factors regulating the formation of chylomicrons and very-low-density lipoproteins by the rat small intestine.

1 reference

12 December 2020

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep.

1 reference

12 December 2020

Portal venous transport of long-chain fatty acids absorbed from rat intestine.

1 reference

12 December 2020

The cellular fatty acid binding proteins: aspects of structure, regulation, and function

1 reference

12 December 2020

An Acute and Coincident Increase in FABP Expression and Lymphatic Lipid and Drug Transport Occurs During Intestinal Infusion of Lipid-Based Drug Formulations to Rats

1 reference

12 December 2020

Biopharmaceutical challenges associated with drugs with low aqueous solubility--the potential impact of lipid-based formulations.

1 reference

12 December 2020

Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor

1 reference

12 December 2020

New insights into the fatty acid-binding protein (FABP) family in the small intestine

1 reference

12 December 2020

Intestinal triglycerides are derived from both endogenous and exogenous sources

1 reference

12 December 2020

Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs

1 reference

12 December 2020

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

1 reference

12 December 2020

Prechylomicron transport vesicle: isolation and partial characterization

1 reference

12 December 2020

The role of lymphoid organs in the immunopathogenesis of HIV infection.

1 reference

12 December 2020

A proposed model for the assembly of chylomicrons

1 reference

12 December 2020

Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay.

1 reference

12 December 2020

Differences in the Intestinal Absorption of Saturated and Unsaturated Long Chain Fatty Acids

1 reference

12 December 2020

CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

1 reference

12 December 2020

Coassimilation of dietary fat and benzo(a)pyrene in the small intestine: an absorption model using the killifish.

1 reference

12 December 2020

Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells

1 reference

12 December 2020

Evidence for vesicles that mediate long-chain fatty acid uptake by human microvascular endothelial cells.

1 reference

12 December 2020

The Metabolic Fate of Lysolecithin Administered into Rat Duodenal Lumen

1 reference

12 December 2020

Triglyceride biosynthesis in the intestinal mucosa

1 reference

12 December 2020

A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids

1 reference

12 December 2020

Influence of dietary fat saturation on lipid absorption in the rat

1 reference

12 December 2020

A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine.

1 reference

12 December 2020

Mechanism of the intestinal absorption of drugs from oil-in-water emulsions. VII. Role of bile in the lymphatic transport of lipid-soluble compounds from triolein emulsions

1 reference

12 December 2020

Intracellular movement of triacylglycerols in the intestine

1 reference

12 December 2020

10.1016/J.ADDR.2007.09.007

Identifiers

DOI

1 reference

17 August 2017

1 reference