Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line (Q37057444)

18 August 2017

Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line (English)

1 reference

18 August 2017

0 references

0 references

1 reference

1 reference

1 reference

4

Rebecca L Cunningham

1 reference

18 August 2017

Shaletha Holmes

1

1 reference

18 August 2017

Meharvan Singh

series ordinal

2

1 reference

18 August 2017

Chang Su

series ordinal

3

1 reference

18 August 2017

language of work or name

English

0 references

publication date

11 May 2016

1 reference

18 August 2017

1 reference

18 August 2017

157

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18 August 2017

7

1 reference

18 August 2017

2824-2835

1 reference

describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4929547/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor

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Androgens exacerbate motor asymmetry in male rats with unilateral 6-hydroxydopamine lesion

29 September 2017

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Caffeic acid phenethyl ester suppresses eotaxin secretion and nuclear p-STAT6 in human lung fibroblast cells

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Androgen decreases dopamine neurone survival in rat midbrain

29 September 2017

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29 September 2017

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Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta

29 September 2017

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29 September 2017

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Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration

29 September 2017

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29 September 2017

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Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome

29 September 2017

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Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

29 September 2017

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Postmenopausal estrogen use affects risk for Parkinson disease

29 September 2017

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Neuroinflammation, COX-2, and ALS--a dual role?

29 September 2017

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29 September 2017

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Parkinson's disease: mechanisms and models

29 September 2017

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Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity

29 September 2017

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

29 September 2017

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Oxidative stress in Parkinson's disease

29 September 2017

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29 September 2017

Androgens and aging men.

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29 September 2017

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Cyclooxygenase inhibition as a strategy to ameliorate brain injury.

29 September 2017

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Relative androgen excess and increased cardiovascular risk after menopause: a hypothesized relation

29 September 2017

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Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier

29 September 2017

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Mechanism of action of acetaminophen: is there a cyclooxygenase 3?

29 September 2017

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Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging.

29 September 2017

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Ibuprofen protects dopaminergic neurons against glutamate toxicity in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

29 September 2017

1 reference

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Gender differences in brain and behavior: hormonal and neural bases

29 September 2017

1 reference

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Immortalized dopamine neurons: A model to study neurotoxicity and neuroprotection

29 September 2017

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Is NF-kappaB the sensor of oxidative stress?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

29 September 2017

1 reference

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Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

29 September 2017

1 reference

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NF-kappa B: a crucial transcription factor for glial and neuronal cell function

29 September 2017

1 reference

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

29 September 2017

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Gene expression of the transcription factor NF-kappa B in hippocampus: regulation by synaptic activity

29 September 2017

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Toxicity of iron and hydrogen peroxide: the Fenton reaction

29 September 2017

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NF-kappa B: a lesson in family values

29 September 2017

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

29 September 2017

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Biological Actions of Androgens

29 September 2017

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Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

29 September 2017

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The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein

29 September 2017

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Adrenal Function in Normal Women and Women with the Poly cystic Ovary Syndrome*

29 September 2017

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Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.

29 September 2017

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MPP(+)-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Linking selective vulnerability to cell death mechanisms in Parkinson's disease

27 June 2018

1 reference

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An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

27 June 2018

1 reference

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Cyclooxygenases and the central nervous system

27 June 2018

1 reference

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Mechanism of action of aspirin-like drugs

27 June 2018

1 reference

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Selective colocalization of immunoreactivity for intracellular gonadal hormone receptors and tyrosine hydroxylase in the ventral tegmental area, substantia nigra, and retrorubral fields in the rat.

27 June 2018

1 reference

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Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Steroid and gonadotropin levels in women during the peri-menopausal years

27 June 2018

1 reference

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Superoxide sensitivity of the Escherichia coli aconitase.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Naproxen sodium decreases prostaglandins secretion from cultured human endometrial stromal cells modulating metabolizing enzymes mRNA expression

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Caffeic acid phenethyl ester (CAPE) protects PC12 cells from MPP+ toxicity by inducing the expression of neuron-typical proteins

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Advanced oxidation protein products are increased in women with polycystic ovary syndrome: relationship with traditional and nontraditional cardiovascular risk factors in patients with polycystic ovary syndrome

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929547

Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes

4 September 2018

1 reference

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Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system

4 September 2018

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Circulating bioactive androgens in midlife women.

4 September 2018

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Behaviour of some indicators of oxidative stress in postmenopausal and fertile women.

4 September 2018

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Gender and the Parkinson's disease phenotype

4 September 2018

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Dopaminergic neurotoxicity by 6-OHDA and MPP+: differential requirement for neuronal cyclooxygenase activity

4 September 2018

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Clinical trials. Halt of Celebrex study threatens drug's future, other trials

4 September 2018

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Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse

4 September 2018

1 reference

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Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea

4 September 2018

1 reference

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Risk of Parkinson disease in women: effect of reproductive characteristics.

4 September 2018

1 reference

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Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells

4 September 2018

1 reference

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Sex differences in androgen and estrogen receptor expression in rat substantia nigra during development: an immunohistochemical study

4 September 2018

1 reference

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Vascular reactivity in hypogonadal men is reduced by androgen substitution

4 September 2018

1 reference

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Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.

4 September 2018

1 reference

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Construction and field validation of a self-administered screener for testosterone deficiency (hypogonadism) in ageing men.

4 September 2018

1 reference

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Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men.

4 September 2018

1 reference

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Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons

4 September 2018

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12 December 2020

Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia

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12 December 2020

Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

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12 December 2020

Histochemical detection of apoptosis in Parkinson's disease.

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12 December 2020

Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease

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12 December 2020

Baseline Characteristics of Participants in the Women's Health Study

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12 December 2020

A Population-Based Investigation of Parkinson's Disease With and Without Dementia

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12 December 2020

Age at menopause predicts age at onset of Parkinson's disease

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12 December 2020

Identifiers

DOI

10.1210/EN.2015-1738

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

27167771

1 reference