Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR (Q37129376)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19234131%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR (English)

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22 January 2020

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5

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22 January 2020

author name string

Khalid Al-Nedawi

1

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22 January 2020

Brian Meehan

2

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22 January 2020

Robert S Kerbel

3

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22 January 2020

Anthony C Allison

4

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22 January 2020

language of work or name

English

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publication date

20 February 2009

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22 January 2020

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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22 January 2020

volume

106

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22 January 2020

issue

10

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22 January 2020

page(s)

3794-3799

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

22 January 2020

cites work

1 reference

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Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors

14 September 2017

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Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

14 September 2017

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Ceramide triggers budding of exosome vesicles into multivesicular endosomes

14 September 2017

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New phosphatidylserine receptors: clearance of apoptotic cells and more

14 September 2017

1 reference

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Identification of Tim4 as a phosphatidylserine receptor

14 September 2017

1 reference

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Tumour-released exosomes and their implications in cancer immunity.

14 September 2017

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The role of the EGFR signaling in tumor microenvironment.

14 September 2017

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Autocrine VEGF signaling is required for vascular homeostasis

14 September 2017

1 reference

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Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer

14 September 2017

1 reference

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

14 September 2017

1 reference

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Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells

14 September 2017

1 reference

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The emerging shape of the ESCRT machinery

14 September 2017

1 reference

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EGF-ERBB signalling: towards the systems level

14 September 2017

1 reference

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Exosomes biological significance: A concise review

14 September 2017

1 reference

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Emission of membrane vesicles: roles in complement resistance, immunity and cancer

14 September 2017

1 reference

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The P-selectin, tissue factor, coagulation triad

14 September 2017

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Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

14 September 2017

1 reference

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Acute cholesterol depletion impairs functional expression of tissue factor in fibroblasts: modulation of tissue factor activity by membrane cholesterol

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Dual mechanism of vascular endothelial growth factor upregulation by hypoxia in human hepatocellular carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Purification, characterization and biological significance of tumor-derived exosomes.

14 September 2017

1 reference

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A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation.

14 September 2017

1 reference

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Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Interaction of an annexin V homodimer (Diannexin) with phosphatidylserine on cell surfaces and consequent antithrombotic activity.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Expression of vascular endothelial growth factor in uveal melanoma is independent of 6p21-region copy number.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Tumor-associated endothelial cells with cytogenetic abnormalities.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656159

Mast cell-derived exosomes activate endothelial cells to secrete plasminogen activator inhibitor type 1

3 September 2018

1 reference

12 December 2020

Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029

1 reference

12 December 2020

Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis

1 reference

12 December 2020

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast

1 reference

12 December 2020

Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells.

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0804543106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19234131%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19234131%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

19234131

1 reference