Immunosuppression routed via the kynurenine pathway: a biochemical and pathophysiologic approach. (Q37144901)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18429497%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

review article

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title

Immunosuppression routed via the kynurenine pathway: a biochemical and pathophysiologic approach (English)

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6 January 2020

1 reference

1 reference

Ignacio Melero, MD-PhD

5

object named as

Ignacio Melero

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6 January 2020

author name string

Alvaro González

1

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6 January 2020

Nerea Varo

2

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6 January 2020

Estibaliz Alegre

3

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6 January 2020

Angel Díaz

4

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6 January 2020

publication date

1 January 2008

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Advances in Clinical Chemistry

6 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18429497%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

45

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6 January 2020

page(s)

155-197

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Tolerance, suppression and the fetal allograft

6 January 2020

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Indoleamine 2,3-dioxygenase expression in monocytes of healthy nonpregnant women after induction with human choriongonadotropine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Decreased tryptophan catabolism by placental indoleamine 2,3-dioxygenase in preeclampsia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Measurement of tryptophan, kynurenine and neopterin in women with and without postpartum blues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

IDO expression on decidual and peripheral blood dendritic cells and monocytes/macrophages after treatment with CTLA-4 or interferon-gamma increase in normal pregnancy but decrease in spontaneous abortion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3 dioxygenase and human leucocyte antigen-G inhibit the T-cell alloproliferative response through two independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Linking two immuno-suppressive molecules: indoleamine 2,3 dioxygenase can modify HLA-G cell-surface expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

HLA-G molecules: from maternal-fetal tolerance to tissue acceptance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

The metabolism of tryptophan. 2. The metabolism of tryptophan in patients suffering from cancer of the bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Characteristics of interferon induced tryptophan metabolism in human cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

In vivo uptake and metabolism of alpha-[11C]methyl-L-tryptophan in human brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Tumor-driven evolution of immunosuppressive networks during malignant progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Cancer immunoediting: from immunosurveillance to tumor escape

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Marrying immunotherapy with chemotherapy: why say IDO?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Cytoplasmic transport of Stat3 by receptor-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Inhibition of interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung by inhibitors of prostaglandin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

IDO and tolerance to tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Immunoactivative role of indoleamine 2,3-dioxygenase in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Should sentinel lymph-node biopsy be used routinely for staging melanoma and breast cancers?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Weight loss in patients with hematological neoplasias is associated with immune system stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Tryptophan and quality of life in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Tryptophan degradation in patients with gynecological cancer correlates with immune activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Interferon-beta affects the tryptophan metabolism in multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Cellular immune responses to HIV.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Neopterin in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Immune activation and degradation of tryptophan in coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Crucial role of interferon-gamma and stimulated macrophages in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

The neurobiology of tryptophan depletion in depression: effects of intravenous tryptophan infusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Neopterin production, tryptophan degradation, and mental depression--what is the link?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Neuroimmune-endocrine crosstalk in schizophrenia and mood disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Kynurenine metabolites of tryptophan: implications for neurologic diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Interleukin-2 and -6 induce behavioral-activating effects in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

Simultaneous measurement of kynurenine and tryptophan in human plasma and supernatants of cultured human cells by HPLC with coulometric detection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2423%2807%2900007-8

7 January 2021

10.1016/S0065-2423(07)00007-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18429497%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference