Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry. (Q37171046)

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scientific article published on 23 January 2013

Language	Label	Description	Also known as
English	Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.	scientific article published on 23 January 2013

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scholarly article

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22 February 2020

Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry (English)

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22 February 2020

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hepatocellular carcinoma

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based on heuristic

inferred from title

6

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22 February 2020

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22 February 2020

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Ming-Luan Chen

1

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22 February 2020

Fan Shen

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22 February 2020

Wei Huang

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22 February 2020

Jia-Hui Qi

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22 February 2020

Yinsheng Wang

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22 February 2020

Song-Mei Liu

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22 February 2020

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23 January 2013

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22 February 2020

Clinical Chemistry

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22 February 2020

59

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22 February 2020

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22 February 2020

824-832

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22 February 2020

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

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Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation

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Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers.

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5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations

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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

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Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes

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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

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A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples

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Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

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Epigenetic modifications and human disease

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Epigenomics reveals a functional genome anatomy and a new approach to common disease

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Active DNA demethylation: many roads lead to Rome.

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

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Active DNA demethylation mediated by DNA glycosylases

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Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

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Epigenetic gene silencing in cancer: the DNA hypermethylome

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Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.

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Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine

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Protein Digest Analysis by Pressurized Capillary Electrochromatography Using an Ion Trap Storage/Reflectron Time-of-Flight Mass Detector

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12 December 2020

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