Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3(H2O). (Q37200463)

18 August 2017

Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3(H2O). (English)

1 reference

18 August 2017

Gurpanna Saggu

1

1 reference

18 August 2017

Claudio Cortes

2

1 reference

18 August 2017

Heather N Emch

3

1 reference

18 August 2017

Galia Ramirez

4

1 reference

18 August 2017

Randall G Worth

5

1 reference

18 August 2017

Viviana P Ferreira

6

1 reference

18 August 2017

language of work or name

English

0 references

publication date

15 May 2013

1 reference

18 August 2017

Journal of Immunology

1 reference

18 August 2017

190

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18 August 2017

12

1 reference

18 August 2017

6457-6467

1 reference

Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Monitoring and modeling treatment of atypical hemolytic uremic syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The tick-over theory revisited: is C3 a contact-activated protein?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Native properdin binds to Chlamydia pneumoniae and promotes complement activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement: a key system for immune surveillance and homeostasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement activation on platelets: implications for vascular inflammation and thrombosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

An evaluation of the role of properdin in alternative pathway activation on Neisseria meningitidis and Neisseria gonorrhoeae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Platelets and innate immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Platelet-associated complement factor H in healthy persons and patients with atypical HUS.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Factor H dysfunction in patients with atypical hemolytic uremic syndrome contributes to complement deposition on platelets and their activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Factor H mediated cell surface protection from complement is critical for the survival of PNH erythrocytes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Kinetic studies on the interactions of heparin and complement proteins using surface plasmon resonance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Platelet activation leads to activation and propagation of the complement system

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Factor H binds to washed human platelets.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Does properdin crosslink the cellular and the humoral immune response?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Increased platelet deposition on atherosclerotic coronary arteries

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Characterization of mutant forms of recombinant human properdin lacking single thrombospondin type I repeats. Identification of modules important for function.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Human complement in the arachidonic acid transformation pathway in platelets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Human platelet activation by C3a and C3a des-arg

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Interactions of the platelets in paroxysmal nocturnal hemoglobinuria with complement. Relationship to defects in the regulation of complement and to platelet survival in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Human complement in thrombin-mediated platelet function: uptake of the C5b-9 complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement activation by tubular cells is mediated by properdin binding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

A novel mechanism of alternative pathway complement activation accounts for the deposition of C3 fragments on CR2-expressing homologous cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Platelet hyperreactivity and prognosis in survivors of myocardial infarction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Proteome changes in platelets activated by arachidonic acid, collagen, and thrombin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

C3 proactivator convertase and its mode of action

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Purification and characterization of human platelet proteoglycan

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Resolution and analysis of 'native' and 'activated' properdin

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Isolation and characterization of the complement-inhibiting protein CD59 antigen from platelet membranes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Characterization of the sulfated glycosaminoglycan on the surface and in the storage granules of rabbit platelets

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The amplification loop of the complement pathways.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Factor H binds to platelet integrin alphaIIbbeta3.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The complement factor properdin induces formation of platelet-leukocyte aggregates via leukocyte activation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Blood platelets activate the classical pathway of human complement.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

The endothelium as physiological source of properdin: role of wall shear stress.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

C5 convertase of the alternative pathway of complement. Kinetic analysis of the free and surface-bound forms of the enzyme

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784323

Properdin binds to sulfatide [Gal(3-SO4)beta 1-1 Cer] and has a sequence homology with other proteins that bind sulfated glycoconjugates

3 September 2018

1 reference

12 December 2020

Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils

1 reference

12 December 2020

A fluorimetric assay for native C3. The hemolytically active form of the third component of human complement

1 reference

12 December 2020

Analysis of the natural polymeric forms of human properdin and their functions in complement activation

1 reference

12 December 2020

Activation of the alternative complement pathway: recognition of surface structures on activators by bound C3b

1 reference

12 December 2020

Complement alternative pathway acts as a positive feedback amplification of neutrophil activation

1 reference

12 December 2020

Eicosanoids and iso-eicosanoids: constitutive, inducible and transcellular biosynthesis in vascular disease

1 reference

12 December 2020

In the shadow of the thrombus

1 reference

12 December 2020

Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation

1 reference

12 December 2020

Deficiency of the complement regulatory protein, "decay-accelerating factor," on membranes of granulocytes, monocytes, and platelets in paroxysmal nocturnal hemoglobinuria

1 reference

12 December 2020

Increased neutrophil-platelet adhesion in patients with unstable angina

1 reference

12 December 2020

Platelet activity in vivo in hyperlipoproteinemia--importance of combined hyperlipidemia

1 reference

12 December 2020

Activation of human platelets through gp140, the C3d/EBV receptor (CR2)

1 reference

12 December 2020

1 reference

12 December 2020

Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease

1 reference

12 December 2020

Critical role of the C-terminal domains of factor H in regulating complement activation at cell surfaces

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1300610

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

23677468

1 reference