Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines (Q37218585)

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scientific article published on 12 September 2008

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English	Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines	scientific article published on 12 September 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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lipopolysaccharide

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author name string

Christopher J Henry

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yan Huang

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Angela M Wynne

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jonathan P Godbout

4

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Europe PubMed Central

PMC publication ID

19 August 2017

publication date

12 September 2008

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Europe PubMed Central

PMC publication ID

19 August 2017

Brain, Behavior, and Immunity

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Europe PubMed Central

PMC publication ID

19 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

309-317

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

1 reference

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Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.

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Microglia biology in health and disease.

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Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

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Brain-immune communication pathways

1 reference

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Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

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Isolation of murine microglial cells for RNA analysis or flow cytometry

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Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII

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An age-related decline in interleukin-10 may contribute to the increased expression of interleukin-6 in brain of aged mice

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Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kappaB-induced CCAAT/enhancer-binding protein delta in mouse macrophages

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NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages

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Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared

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The unresponsiveness of aged mice to polysaccharide antigens is a result of a defect in macrophage function

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Increased microglial activation and protein nitration in white matter of the aging monkey☆

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10.1016/J.BBI.2008.09.002

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Europe PubMed Central

PMC publication ID

19 August 2017

release_tspq4zkko5heboaq53qzx23asi

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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