Progeroid syndromes: probing the molecular basis of aging? (Q37229309)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9497912%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

Progeroid syndromes: probing the molecular basis of aging? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9497912%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author

Richard G.A. Faragher

series ordinal

2

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10 November 2019

author name string

D Kipling

series ordinal

1

1 reference

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10 November 2019

language of work or name

English

0 references

publication date

1 October 1997

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Journal of Clinical Pathology

10 November 2019

published in

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10 November 2019

volume

50

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10 November 2019

issue

5

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10 November 2019

page(s)

234-241

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

10 November 2019

cites work

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

6 September 2017

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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

6 September 2017

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Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group

6 September 2017

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The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

6 September 2017

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Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

6 September 2017

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Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

6 September 2017

1 reference

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Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts

6 September 2017

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In situ analysis of changes in telomere size during replicative aging and cell transformation

6 September 2017

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Positional cloning of the Werner's syndrome gene

6 September 2017

1 reference

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Role of ceramide in cellular senescence

6 September 2017

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Werner syndrome and biological ageing: a molecular genetic hypothesis

6 September 2017

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The gene responsible for Werner syndrome may be a cell division "counting" gene

6 September 2017

1 reference

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Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein

6 September 2017

1 reference

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Failure of senescent human fibroblasts to express the insulin-like growth factor-1 gene

6 September 2017

1 reference

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Telomere Shortening Is Associated with Cell Division in Vitro and in Vivo

6 September 2017

1 reference

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Elevated expression of mitochondrial cytochrome b and NADH dehydrogenase subunit 4/4L genes in senescent human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo

6 September 2017

1 reference

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A model of clonal attenuation

6 September 2017

1 reference

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Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype

6 September 2017

1 reference

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Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Expression of cell cycle-dependent genes in young and senescent WI-38 fibroblasts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Mutator phenotype of Werner syndrome is characterized by extensive deletions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Genetic and molecular studies of cellular immortalization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Telomere reduction in human colorectal carcinoma and with ageing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Telomeres shorten during ageing of human fibroblasts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Bloom syndrome and ataxia telangiectasia

6 September 2017

1 reference

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Genetic linkage of Werner's syndrome to five markers on chromosome 8

6 September 2017

1 reference

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Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence

6 September 2017

1 reference

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Arteriosclerosis. Impairment of cellular interactions in the arterial wall

6 September 2017

1 reference

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Telomere length predicts replicative capacity of human fibroblasts

6 September 2017

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Xeroderma pigmentosum and Cockayne syndrome: overlapping clinical and biochemical phenotypes

6 September 2017

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High blood pressure: hunting the genes

6 September 2017

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The relationship between in vitro cellular aging and in vivo human age

6 September 2017

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The evolution of ageing and longevity

6 September 2017

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Cataloging altered gene expression in young and senescent cells using enhanced differential display

6 September 2017

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Telomeres and telomerase in aging and cancer

14 September 2017

1 reference

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Origins of G1 arrest in senescent human fibroblasts

14 September 2017

1 reference

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Genetics and aging; the Werner syndrome as a segmental progeroid syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Cycling Werner's syndrome fibroblasts display calcium-dependent potassium currents

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

28 September 2017

1 reference

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Werner syndrome: entering the helicase era.

28 September 2017

1 reference

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Replicative senescence: implications for in vivo aging and tumor suppression

28 September 2017

1 reference

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DNA repair fine structure in Werner's syndrome cell lines.

28 September 2017

1 reference

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28 September 2017

1 reference

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The biology of replicative senescence

28 September 2017

1 reference

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Cyclins, cyclin-dependent kinases and differentiation

26 June 2018

1 reference

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Effects of platelet-derived growth factor on endothelial wound healing of human corneas

26 June 2018

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Expression of 72-kDa gelatinase and TIMP-2 in early and late passage human fibroblasts.

26 June 2018

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Evidence for a critical telomere length in senescent human fibroblasts

26 June 2018

1 reference

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In vitro assessment of keratinocyte aging

26 June 2018

1 reference

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Collagenase production by early and late passage cultures of human fibroblasts

26 June 2018

1 reference

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Immune function, mutant frequency, and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, Cockayne's syndrome, and trichothiodystrophy

26 June 2018

1 reference

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Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

26 June 2018

1 reference

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A mortalization theory for the control of cell proliferation and for the origin of immortal cell lines

26 June 2018

1 reference

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Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

In vitro cellular aging in T-lymphocyte cultures: analysis of DNA content and cell size

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Yeast checkpoint genes in DNA damage processing: implications for repair and arrest

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

A quantitative analysis of the aging of human glial cells in culture

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients.

3 September 2018

1 reference

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Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Accelerated telomere shortening in ataxia telangiectasia

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379638

Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular aging

4 December 2018

1 reference

12 December 2020

Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts

1 reference

12 December 2020

Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum

1 reference

12 December 2020

Progeria, a model disease for the study of accelerated aging

1 reference

12 December 2020

The in vitro replicative potential and cellular morphology of human lens epithelial cells derived from different aged donors

1 reference

12 December 2020

Normal level of unscheduled DNA synthesis in Werner's syndrome fibroblasts in culture

1 reference

12 December 2020

Spontaneous and induced chromosomal instability in Werner syndrome

1 reference

12 December 2020

Human T lymphocytes possess a limited in vitro life span

1 reference

12 December 2020

Senescent human diploid fibroblasts are able to support DNA synthesis and to express markers associated with proliferation

1 reference

12 December 2020

Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts

1 reference

12 December 2020

Evidence for a new step in telomere maintenance

1 reference

12 December 2020

Long-term caloric restriction delays age-related decline in proliferation capacity of murine lens epithelial cells in vitro and in vivo

1 reference

12 December 2020

Matrix stimulates the proliferation of human corneal endothelial cells in culture

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12 December 2020

Human lens epithelial cells in tissue culture

1 reference

12 December 2020

Cloning and expression of SAG: a novel marker of cellular senescence

1 reference

12 December 2020

Loss of transcription factor AP-1 DNA binding activity during lymphocyte aging in vivo

1 reference

12 December 2020

The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture

1 reference

12 December 2020

Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors

1 reference

12 December 2020

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

12 December 2020

Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human cd4+ tcr2+ cultured T cell clones

1 reference

12 December 2020

The division cycle and RNA-synthesis in diploid human cells at different passage levels in vitro

1 reference

12 December 2020

Cellular senescence and DNA synthesis. Thymidine incorporation as a measure of population age in human diploid cells

1 reference

12 December 2020

Attempted hybridizations with senescent human fibroblasts

1 reference

12 December 2020

The Cell Biology of Aging

1 reference

12 December 2020

Identifiers

DOI

10.1136/MP.50.5.234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9497912%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9497912%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

9497912

1 reference