CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. (Q37305045)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19632179%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells (English)

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3 February 2020

1 reference

1 reference

acute myeloid leukemia

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adverse prognostic factor

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3

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3 February 2020

Kenneth D Gibbs

6

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8

Irving L Weissman

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3 February 2020

author name string

Ravindra Majeti

1

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3 February 2020

Mark P Chao

2

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3 February 2020

Wendy W Pang

4

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3 February 2020

Siddhartha Jaiswal

5

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3 February 2020

Nico van Rooijen

7

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language of work or name

English

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publication date

1 July 2009

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3 February 2020

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3 February 2020

volume

138

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issue

2

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page(s)

286-299

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Dysregulated gene expression networks in human acute myelogenous leukemia stem cells

3 February 2020

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CD47 in the immune response: role of thrombospondin and SIRP-alpha reverse signaling

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Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages

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Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

6 September 2017

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The SIRP family of receptors and immune regulation

6 September 2017

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Stem cell research: paths to cancer therapies and regenerative medicine

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Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system

6 September 2017

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

6 September 2017

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

6 September 2017

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Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

6 September 2017

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Stem cells, cancer, and cancer stem cells

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CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

6 September 2017

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Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation

6 September 2017

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CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis

6 September 2017

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

6 September 2017

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AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

6 September 2017

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6 September 2017

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Apoptosis inducing bivalent single-chain antibody fragments against CD47 showed antitumor potency for multiple myeloma.

14 September 2017

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A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells

14 September 2017

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Species- and cell type-specific interactions between CD47 and human SIRPalpha.

14 September 2017

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

26 June 2018

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Monoclonal antibody therapy of cancer

2 September 2018

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12 December 2020

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12 December 2020

Semimature stage: a checkpoint in a dendritic cell maturation program that allows for functional reversion after signal-regulatory protein-alpha ligation and maturation signals

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12 December 2020

An FLT3 gene-expression signature predicts clinical outcome in normal karyotype AML

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12 December 2020

Detection and characterization of primitive malignant and normal progenitors in patients with acute myelogenous leukemia using long-term coculture with supportive feeder layers and cytokines

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12 December 2020

10.1016/J.CELL.2009.05.045

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19632179%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19632179%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

19632179

1 reference