Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents (Q37363590)

19 August 2017

Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents (English)

1 reference

19 August 2017

Wei Feng

1

1 reference

19 August 2017

Mavurapu Satyanarayana

2

1 reference

19 August 2017

Liang Cheng

3

1 reference

19 August 2017

Angela Liu

4

1 reference

19 August 2017

Yuan-Chin Tsai

5

1 reference

19 August 2017

Leroy F Liu

6

1 reference

19 August 2017

Edmond J LaVoie

7

1 reference

19 August 2017

language of work or name

English

0 references

publication date

5 September 2008

1 reference

Bioorganic & Medicinal Chemistry

19 August 2017

1 reference

19 August 2017

16

1 reference

19 August 2017

20

1 reference

19 August 2017

9295-9301

1 reference

Topoisomerase I inhibitors: camptothecins and beyond

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Cellular roles of dna topoisomerases: a molecular perspective

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

DNA topoisomerases: structure, function, and mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Tumor cell death induced by topoisomerase-targeting drugs.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Substituted benz[a]acridines and benz[c]acridines as mammalian topoisomerase poisons

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

DNA topoisomerases: essential enzymes and lethal targets

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

BCRP/MXR/ABCP expression in topotecan-resistant human breast carcinoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752341

Diaza- and triazachrysenes: potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18829334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18829334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMC.2008.09.002

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

18829334

1 reference