scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair (Q37404182)

20 August 2017

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair (English)

1 reference

20 August 2017

Biedermann KA

1

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20 August 2017

Sun JR

2

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20 August 2017

Giaccia AJ

3

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20 August 2017

Tosto LM

4

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20 August 2017

Brown JM

5

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20 August 2017

language of work or name

English

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publication date

1 February 1991

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

88

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20 August 2017

4

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20 August 2017

1394-1397

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A severe combined immunodeficiency mutation in the mouse

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Cell cycle-dependent repair of double-strand DNA breaks in a gamma-ray-sensitive Chinese hamster cell

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The V(D)J recombination activating gene, RAG-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Human chromosome 5 complements the DNA double-strand break-repair deficiency and gamma-ray sensitivity of the XR-1 hamster variant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Repair of Potentially Lethal Radiation DamageIn VitroandIn Vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Asymmetric field inversion gel electrophoresis: a new method for detecting DNA double-strand breaks in mammalian cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The sensitivity of cells from normal mouse bone marrow to gamma radiation in vitro and in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

Evaluation of the mouse mutant "wasted" as an animal model for ataxia telangiectasia. I. Age-dependent and tissue-specific effects

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51024

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement

2 September 2018

1 reference

12 December 2020

A search for radiosensitive mouse mutants by use of the micronucleus technique

1 reference

12 December 2020

Effect of DNA-damaging agents on isolated spleen cells and lung fibroblasts from the mouse mutant "wasted," a putative animal model for ataxia-telangiectasia

1 reference

12 December 2020

Nature of the scid defect: a defective VDJ recombinase system

1 reference

12 December 2020

X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining

1 reference

12 December 2020

The scid mutation in mice causes a general defect in DNA repair

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12 December 2020

Growth of human tumors in immune-deficient scid mice and nude mice

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12 December 2020

Microcolony Survival Assay for Cells of Mouse Intestinal Mucosa Exposed to Radiation

1 reference

12 December 2020

Studies of V(D)J Recombination with Extrachromosomal Substrates

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12 December 2020

The scid mutation disrupts gene rearrangement at the rejoining of coding strands

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12 December 2020

Identifiers

DOI

10.1073/PNAS.88.4.1394

1 reference

release_2p5f37nry5aelic63gn3k2tmoi

20 August 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2p5f37nry5aelic63gn3k2tmoi

24 November 2022

mapped directly with Wikidata item

1 reference

20 August 2017

PubMed publication ID

1996340

1 reference