Small-molecule inhibitors of store-operated calcium entry (Q37426521)

20 August 2017

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title

Small-molecule inhibitors of store-operated calcium entry (English)

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20 August 2017

Zachary K Sweeney

1

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20 August 2017

Ana Minatti

series ordinal

2

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20 August 2017

Donald C Button

series ordinal

3

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20 August 2017

Silvia Patrick

series ordinal

4

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20 August 2017

publication date

1 May 2009

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20 August 2017

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20 August 2017

volume

4

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20 August 2017

issue

5

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20 August 2017

page(s)

706-718

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A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Inhibition by SK&F 96365 of Ca2+ current, IL-2 production and activation in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Extracellular site for econazole-mediated block of Ca2+ release-activated Ca2+ current (Icrac) in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Blocking Ca2+entry: a way to control cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Oligomycin inhibits store-operated channels by a mechanism independent of its effects on mitochondrial ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Myosin light chain kinase regulates capacitative ca(2+) entry in human monocytes/macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Primaquine, an inhibitor of vesicular transport, blocks the calcium-release-activated current in rat megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Store-activated Ca2+ inflow in Xenopus laevis oocytes: inhibition by primaquine and evaluation of the role of membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

Calcium signalling: dynamics, homeostasis and remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Measurements of the free luminal ER Ca(2+) concentration with targeted "cameleon" fluorescent proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Calcium signaling in lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Calcium signalling in lymphocyte activation and disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

The molecular choreography of a store-operated calcium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

New molecular players in capacitative Ca2+ entry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Methods for studying store-operated calcium entry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Automated patch-clamp technique: increased throughput in functional characterization and in pharmacological screening of small-conductance Ca2+ release-activated Ca2+ channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Calcium oscillations in T-cells: mechanisms and consequences for gene expression

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Gene regulation mediated by calcium signals in T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Molecular basis of the CRAC channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

New developments in the signaling mechanisms of the store-operated calcium entry pathway

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

The STIM/Orai coupling machinery.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Orai1 is an essential pore subunit of the CRAC channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

CRACM1 multimers form the ion-selective pore of the CRAC channel.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

CRAC inhibitors: identification and potential

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Orai1 and STIM reconstitute store-operated calcium channel function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Application of intact cell-based NFAT-beta-lactamase reporter assay for Pasteurella multocida toxin-mediated activation of calcium signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Fusions to beta-lactamase as a reporter for gene expression in live mammalian cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Insights into TRPM4 function, regulation and physiological role.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

TH1 and TH2 cytokine inhibition by 3,5-bis(trifluoromethyl)pyrazoles, a novel class of immunomodulators

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Potent inhibition of NFAT activation and T cell cytokine production by novel low molecular weight pyrazole compounds

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

High glucose activates nuclear factor of activated T cells in native vascular smooth muscle

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 1: synthesis and inhibitory activity of 5-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamides

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 2: Synthesis and inhibitory activity of aryl-3-trifluoromethylpyrazoles

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: synthesis and CRAC channel inhibitory activity of 4'-[(trifluoromethyl)pyrazol-1-yl]carboxanilides

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Non-specific effects of calcium entry antagonists in mast cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Selective inhibition of thapsigargin-induced contraction and capacitative calcium entry in mouse anococcygeus by trifluoromethylphenylimidazole (TRIM)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Modification of store-operated channel coupling and inositol trisphosphate receptor function by 2-aminoethoxydiphenyl borate in DT40 lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

2-Aminoethyl diphenylborinate analogues: selective inhibition for store-operated Ca2+ entry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Store-operated calcium entry mediates intracellular alkalinization, ERK1/2, and Akt/PKB phosphorylation in bovine neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Inhibition of capacitative Ca2+ entry by a Cl- channel blocker in human endothelial cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Properties of Ca(2+) release-activated Ca(2+) channel block by 5-nitro-2-(3-phenylpropylamino)-benzoic acid in Jurkat cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A novel mechanism for the store-operated calcium influx pathway

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

How strict is the correlation between STIM1 and Orai1 expression, puncta formation, and ICRAC activation?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Effect of nifedipine on capacitive calcium entry in Jurkat T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Unique properties of the capacitative Ca(2+)-entry antagonist LU 52396: its inhibitory activity depends on the activation state of the cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

A role for voltage gated T-type calcium channels in mediating "capacitative" calcium entry?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Differential effects of intravenous anesthetics on capacitative calcium entry in human pulmonary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Morphological changes of T cells following formation of the immunological synapse modulate intracellular calcium signals

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

The blockade of cyclopiazonic acid-induced store-operated Ca2+ entry pathway by YC-1 in neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Lipid bilayer-mediated regulation of ion channel function by amphiphilic drugs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

How highly charged anionic lipids bind and regulate ion channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Inhibition of store-dependent capacitative Ca2+ influx by unsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Progesterone inhibits capacitative Ca2+ entry in Jurkat T lymphocytes by a membrane delimited mechanism, independently of plasma membrane depolarization

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Primaquine revisited six decades after its discovery

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800452

7 January 2021

Identifiers

DOI

10.1002/CMDC.200800452

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20 August 2017

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