Dynein dysfunction induces endocytic pathology accompanied by an increase in Rab GTPases: a potential mechanism underlying age-dependent endocytic dysfunction (Q37431510)

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scientific article published on 15 September 2009

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English	Dynein dysfunction induces endocytic pathology accompanied by an increase in Rab GTPases: a potential mechanism underlying age-dependent endocytic dysfunction	scientific article published on 15 September 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Dynein dysfunction induces endocytic pathology accompanied by an increase in Rab GTPases: a potential mechanism underlying age-dependent endocytic dysfunction (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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author name string

Nobuyuki Kimura

1

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Europe PubMed Central

PMC publication ID

20 August 2017

Makoto Inoue

2

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Europe PubMed Central

PMC publication ID

20 August 2017

Sachi Okabayashi

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Fumiko Ono

4

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Europe PubMed Central

PMC publication ID

20 August 2017

Takayuki Negishi

5

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Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

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publication date

15 September 2009

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Europe PubMed Central

PMC publication ID

20 August 2017

number of pages

12

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Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

20 August 2017

284

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Europe PubMed Central

PMC publication ID

20 August 2017

45

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

31291-31302

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects

1 reference

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SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

1 reference

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The concentration of Nuf, a Rab11 effector, at the microtubule-organizing center is cell cycle regulated, dynein-dependent, and coincides with furrow formation

1 reference

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Huntingtin facilitates dynein/dynactin-mediated vesicle transport.

1 reference

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Rab proteins, connecting transport and vesicle fusion

1 reference

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Dynein mutations impair autophagic clearance of aggregate-prone proteins

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Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP

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Late endosome motility depends on lipids via the small GTPase Rab7.

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The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

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Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170

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Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

1 reference

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1 reference

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Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued

1 reference

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Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein

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Age-dependent uptake and retrograde axonal transport of exogenous albumin and transferrin in rat motor neurons

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Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex

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Identifiers

10.1074/JBC.M109.012625

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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