Sensors of the innate immune system: their mode of action (Q37549926)

21 August 2017

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title

Sensors of the innate immune system: their mode of action (English)

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21 August 2017

6

Bruce Beutler

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21 August 2017

Rosana Gonzalez-Quintial

2

object named as

Rosana Gonzalez-Quintial

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21 August 2017

Roberto Baccala

1

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21 August 2017

Brian R Lawson

3

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21 August 2017

Michael E Stern

4

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21 August 2017

Dwight H Kono

5

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21 August 2017

Argyrios N Theofilopoulos

7

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21 August 2017

language of work or name

English

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publication date

14 July 2009

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Nature Reviews Rheumatology

21 August 2017

published in

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21 August 2017

volume

5

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21 August 2017

issue

8

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21 August 2017

page(s)

448-456

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Approaching the asymptote? Evolution and revolution in immunology

21 August 2017

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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Toll-like receptors and innate immunity

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Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

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Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

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Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity

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Toll-like receptors in systemic autoimmune disease

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Characterization of heme as activator of Toll-like receptor 4.

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Toll-like receptors: structural pieces of a curve-shaped puzzle

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Structures of the toll-like receptor family and its ligand complexes

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The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

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Signalling adaptors used by Toll-like receptors: an update.

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Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

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The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

31 March 2020

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

31 March 2020

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Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins

31 March 2020

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The negative regulation of Toll-like receptor and associated pathways

31 March 2020

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Immunobiology of the TAM receptors

31 March 2020

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

31 March 2020

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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

31 March 2020

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Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins

31 March 2020

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Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages

31 March 2020

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

31 March 2020

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

31 March 2020

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

31 March 2020

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Cathepsins are required for Toll-like receptor 9 responses

31 March 2020

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Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

31 March 2020

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Autophagy-dependent viral recognition by plasmacytoid dendritic cells

31 March 2020

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IMMUNOLOGY: Eating In to Avoid Infection

31 March 2020

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Toll-like receptor signaling in the lysosomal pathways

31 March 2020

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MDA5/RIG-I and virus recognition.

31 March 2020

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Regulation of mitochondrial antiviral signaling pathways

31 March 2020

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RNA recognition and signal transduction by RIG-I-like receptors

31 March 2020

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Approaching the RNA ligand for RIG-I?

31 March 2020

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TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

31 March 2020

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The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

31 March 2020

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

31 March 2020

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NLRX1 is a regulator of mitochondrial antiviral immunity

31 March 2020

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Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

31 March 2020

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Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

31 March 2020

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

31 March 2020

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

31 March 2020

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

CATERPILLERs, pyrin and hereditary immunological disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Intracellular NOD-like receptors in host defense and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

From inflammasomes to fevers, crystals and hypertension: how basic research explains inflammatory diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Mammalian NLR proteins; discriminating foe from friend

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Nod-like proteins in immunity, inflammation and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Liaisons dangereuses: P2X(7) and the inflammasome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

SGT1 is essential for Nod1 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Role for erbin in bacterial activation of Nod2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Cryopyrin activates the inflammasome in response to toxins and ATP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Intracellular pattern recognition receptors in the host response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The inflammasome: first line of the immune response to cell stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Gout-associated uric acid crystals activate the NALP3 inflammasome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The inflammasome: a danger sensing complex triggering innate immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Inflammasomes: guardians of cytosolic sanctity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Rapid secretion of interleukin-1beta by microvesicle shedding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

Stimulation of P2 receptors causes release of IL-1 -loaded microvesicles from human dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

NLRs at the intersection of cell death and immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.136

31 March 2020

Identifiers

DOI

10.1038/NRRHEUM.2009.136

1 reference

Dimensions Publication ID

21 August 2017

1039961355

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1 reference