Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction (Q37557593)

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English	Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction	scientific article published on January 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

19621976

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21 August 2017

review article

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Europe PubMed Central

title

Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction (English)

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Europe PubMed Central

PubMed publication ID

19621976

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21 August 2017

main subject

attention deficit hyperactivity disorder

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attention

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inferred from title

pathophysiology

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based on heuristic

inferred from title

author name string

Amy F T Arnsten

series ordinal

1

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Europe PubMed Central

PubMed publication ID

19621976

retrieved

21 August 2017

publication date

1 January 2009

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stated in

Europe PubMed Central

PubMed publication ID

19621976

retrieved

21 August 2017

published in

CNS Drugs

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Europe PubMed Central

PubMed publication ID

19621976

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21 August 2017

volume

23 Suppl 1

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Europe PubMed Central

PubMed publication ID

19621976

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21 August 2017

page(s)

33-41

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Europe PubMed Central

PubMed publication ID

19621976

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21 August 2017

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Selective deficit in no-go performance induced by blockade of prefrontal cortical alpha 2-adrenoceptors in monkeys

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A randomized, double-blind, placebo-controlled study of guanfacine extended release in children and adolescents with attention-deficit/hyperactivity disorder

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Cortical thinning of the attention and executive function networks in adults with attention-deficit/hyperactivity disorder

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Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder

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The alpha-2A adrenoceptor agonist guanfacine improves sustained attention and reduces overactivity and impulsiveness in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

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Dopamine D4 receptors modulate GABAergic signaling in pyramidal neurons of prefrontal cortex.

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Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals

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Molecular genetics of attention-deficit/hyperactivity disorder

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Molecular genetics of attention

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Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder

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Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function

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D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines

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Role of human prefrontal cortex in attention control.

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Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder

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Responses to methylphenidate in Attention-Deficit/Hyperactivity Disorder and normal children: update 2002

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Disorder-specific dissociation of orbitofrontal dysfunction in boys with pure conduct disorder during reward and ventrolateral prefrontal dysfunction in boys with pure ADHD during sustained attention

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Structural brain imaging of attention-deficit/hyperactivity disorder

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Comparing guanfacine and dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder

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Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder

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A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder

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Locomotor hyperactivity induced by blockade of prefrontal cortical alpha2-adrenoceptors in monkeys

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Basal ganglia and cerebellar loops: motor and cognitive circuits

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Fundamentals of attention-deficit/hyperactivity disorder: circuits and pathways.

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Distribution of dopaminergic receptors in the primate cerebral cortex: quantitative autoradiographic analysis using [3H]raclopride, [3H]spiperone and [3H]SCH23390.

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Medetomidine, atipamezole, and guanfacine in delayed response performance of aged monkeys

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Frontostriatal connectivity and its role in cognitive control in parent-child dyads with ADHD.

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Prefrontal cortex gating of auditory transmission in humans

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Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey

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Delineation of rat kidney α2A- and α2B-adrenoeeptors with [3H]RX821002 radiollgand binding: computer modelling reveals that guanfacine is an α2A-selective compound

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Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation

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Clonidine binds to imidazole binding sites as well as alpha 2-adrenoceptors in the ventrolateral medulla

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https://pubmed.ncbi.nlm.nih.gov/19621976

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Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam.

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PubMed

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Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

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Functional neuroimaging of attention-deficit/hyperactivity disorder: a review and suggested future directions

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https://pubmed.ncbi.nlm.nih.gov/19621976

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Methylphenidate improves prefrontal cortical cognitive function through alpha2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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Dissociation of object and spatial visual processing pathways in human extrastriate cortex

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alpha2-Adrenergic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: emerging concepts from new data

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Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates

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The neural correlates of attention deficit hyperactivity disorder: an ALE meta-analysis

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Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection

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12 December 2020

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Depressed Dopamine Activity in Caudate and Preliminary Evidence of Limbic Involvement in Adults With Attention-Deficit/Hyperactivity Disorder

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DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study.

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The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys.

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Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications

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12 December 2020

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Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task

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12 December 2020

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Catecholamine and second messenger influences on prefrontal cortical networks of "representational knowledge": a rational bridge between genetics and the symptoms of mental illness

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12 December 2020

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Effects of parietal injury on covert orienting of attention.

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12 December 2020

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The alpha-2A noradrenergic receptor agonist guanfacine improves visual object discrimination reversal performance in aged rhesus monkeys

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

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Delayed-response deficit induced by local injection of the alpha 2-adrenergic antagonist yohimbine into the dorsolateral prefrontal cortex in young adult monkeys.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

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Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The −1021 C/T DBH polymorphism is associated with neuropsychological performance among children and adolescents with ADHD

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

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inferred from PubMed ID database lookup

Selective D2 receptor actions on the functional circuitry of working memory

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12 December 2020

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inferred from PubMed ID database lookup

Effects of guanfacine on three forms of distraction in the aging macaque

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

based on heuristic

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Attention and executive systems abnormalities in adults with childhood ADHD: A DT-MRI study of connections

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19621976

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12 December 2020

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Identifiers

DOI

10.2165/00023210-200923000-00005

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19621976

retrieved

21 August 2017

Dimensions Publication ID

1017317295

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release_o6yhsggl4rfgjfljilmhz2z3oi

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PubMed publication ID

19621976

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19621976

retrieved

21 August 2017

 

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