The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation (Q37635718)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8076596%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

title

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation (English)

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24 October 2019

4

J Schlessinger

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24 October 2019

author name string

D M Desai

1

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24 October 2019

J Sap

2

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24 October 2019

O Silvennoinen

3

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24 October 2019

A Weiss

5

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24 October 2019

language of work or name

English

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publication date

1 September 1994

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24 October 2019

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24 October 2019

volume

13

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24 October 2019

issue

17

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24 October 2019

page(s)

4002-4010

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CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line

24 October 2019

cites work

1 reference

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Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases

23 August 2017

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Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor

23 August 2017

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Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

23 August 2017

1 reference

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CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases

23 August 2017

1 reference

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Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase

23 August 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

23 August 2017

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23 August 2017

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23 August 2017

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Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

23 August 2017

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Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

23 August 2017

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23 August 2017

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Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells

23 August 2017

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Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain

23 August 2017

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Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase

23 August 2017

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The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities

23 August 2017

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Oncogenes and signal transduction

23 August 2017

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

23 August 2017

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The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence

23 August 2017

1 reference

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CSK: a protein-tyrosine kinase involved in regulation of src family kinases

23 August 2017

1 reference

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Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

23 August 2017

1 reference

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Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR

23 August 2017

1 reference

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Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

23 August 2017

1 reference

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A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate

23 August 2017

1 reference

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Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells

23 August 2017

1 reference

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CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli

23 August 2017

1 reference

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Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes

23 August 2017

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

23 August 2017

1 reference

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CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx

23 August 2017

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CD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling

23 August 2017

1 reference

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1002 protein phosphatases?

23 August 2017

1 reference

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

23 August 2017

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The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells

23 August 2017

1 reference

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CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

6 September 2017

1 reference

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The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

14 September 2017

1 reference

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The when and how of Src regulation

14 September 2017

1 reference

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CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Demonstration of protein tyrosine phosphatase activity in the second of two homologous domains of CD45.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Transfer of proteins to membranes facilitates both cyanogen bromide cleavage and two-dimensional proteolytic mapping

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Three receptor-linked protein-tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryo

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Two Drosophila receptor-like tyrosine phosphatase genes are expressed in a subset of developing axons and pioneer neurons in the embryonic CNS

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from Escherichia coli expression systems: purification and characterization for specificity and mechanism

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

CD45-negative mutants of a rat natural killer cell line fail to lyse tumor target cells.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395320

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1 September 2018

1 reference

12 December 2020

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1 reference

12 December 2020

Active site labeling of a receptor-like protein tyrosine phosphatase

1 reference

12 December 2020

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

1 reference

12 December 2020

10.1002/J.1460-2075.1994.TB06716.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8076596%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8076596%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

PubMed publication ID

8076596

1 reference