Hormesis is central to toxicology, pharmacology and risk assessment (Q37717844)

22 August 2017

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title

Hormesis is central to toxicology, pharmacology and risk assessment (English)

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22 August 2017

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Edward J Calabrese

1

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22 August 2017

publication date

1 April 2010

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Human & Experimental Toxicology

22 August 2017

published in

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22 August 2017

volume

29

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22 August 2017

issue

4

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22 August 2017

page(s)

249-261

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The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment.

22 August 2017

cites work

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https://api.crossref.org/works/10.1177%2F0960327109363973

Getting the dose-response wrong: why hormesis became marginalized and the threshold model accepted

21 January 2018

1 reference

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Hormesis: why it is important to toxicology and toxicologists

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

The frequency of U-shaped dose responses in the toxicological literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Hormesis and plant biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Prostaglandins: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Nitric oxide: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Androgens: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Adrenergic receptors: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Adenosine: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

5-Hydroxytryptamine (serotonin): biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Dopamine: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Opiates: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Chemotherapeutics and hormesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

21 January 2018

Inorganics and hormesis

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https://api.crossref.org/works/10.1177%2F0960327109363973

Hormetic dose-response relationships in immunology: occurrence, quantitative features of the dose response, mechanistic foundations, and clinical implications

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Neuroscience and hormesis: overview and general findings

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Dose-response features of neuroprotective agents: an integrative summary

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Pharmacological enhancement of neuronal survival

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Enhancing and regulating neurite outgrowth

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Alzheimer's disease drugs: an application of the hormetic dose-response model

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Stress biology and hormesis: the Yerkes-Dodson law in psychology--a special case of the hormesis dose response

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Astrocytes: adaptive responses to low doses of neurotoxins

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

P-glycoprotein efflux transporter activity often displays biphasic dose-response relationships

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

An assessment of anxiolytic drug screening tests: hormetic dose responses predominate

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Modulation of the epileptic seizure threshold: implications of biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Drug therapies for stroke and traumatic brain injury often display U-shaped dose responses: occurrence, mechanisms, and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Pain and u-shaped dose responses: occurrence, mechanisms, and clinical implications

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

U-shaped dose response in behavioral pharmacology: historical foundations

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Addiction and dose response: the psychomotor stimulant theory of addiction reveals that hormetic dose responses are dominant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

State-of-the-science workshop report: issues and approaches in low-dose-response extrapolation for environmental health risk assessment

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

A theory for growth hormesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Evidence that hormesis represents an "overcompensation" response to a disruption in homeostasis.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Hormesis and high-risk groups.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Hormesis in mixtures -- can it be predicted?

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Memory retention: potentiation of cholinergic drug combinations in mice.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Memory enhancement: supra-additive effect of subcutaneous cholinergic drug combinations in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Converging concepts: adaptive response, preconditioning, and the Yerkes-Dodson Law are manifestations of hormesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Transient adaptation to oxidative stress in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

The future of hormesis: where do we go from here?

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

Effect of dexamethasone on cell proliferation of neuroepithelial tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Modulation of fibroblast proliferation by oxygen free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Lymphocyte alteration by procainamide: relation to drug-induced lupus erythematosus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

The relationship between the IC(50), toxic threshold, and the magnitude of stimulatory response in biphasic (hormetic) dose-responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Characterization of U-101017 as a GABA(A) receptor ligand of dual functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

On radiation, paradigms, and hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Are radiation-induced effects hormetic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

A perspective on the scientific, philosophical, and policy dimensions of hormesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327109363973

It's time for a new low-dose-radiation risk assessment paradigm--one that acknowledges hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Low-dose radiation-induced protective process and implications for risk assessment, cancer prevention, and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

Hormesis: how it could affect the risk assessment process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109363973

21 January 2018

Identifiers

DOI

10.1177/0960327109363973

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22 August 2017

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