The Hox genes and their roles in oncogenesis. (Q37722452)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20357775%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

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title

The Hox genes and their roles in oncogenesis (English)

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29 January 2020

1

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29 January 2020

author name string

Saraswati Sukumar

series ordinal

2

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29 January 2020

language of work or name

English

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publication date

1 April 2010

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29 January 2020

published in

Nature Reviews Cancer

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29 January 2020

volume

10

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29 January 2020

issue

5

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29 January 2020

page(s)

361-371

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A model for initiation of mosaic HOX gene expression patterns by non-coding RNAs in early embryos

29 January 2020

cites work

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Sustained expression of homeobox D10 inhibits angiogenesis

21 January 2018

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Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium

21 January 2018

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HOXA10 regulates p53 expression and matrigel invasion in human breast cancer cells

21 January 2018

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PARP inhibitor development for systemic cancer targeting

21 January 2018

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Current Maps of the Location of the Mutant Genes of Drosophila Melanogaster

21 January 2018

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The HOX homeodomain proteins block CBP histone acetyltransferase activity

31 March 2020

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Mutation of HOXA13 in hand-foot-genital syndrome

31 March 2020

1 reference

Mutational analysis of HOXD13 and HOXA13 genes in the triphalangeal thumb-brachyectrodactyly syndrome.

31 March 2020

1 reference

Hox gene function in vertebrate gut morphogenesis: the case of the caecum

31 March 2020

1 reference

Genetics of the female reproductive ducts

31 March 2020

1 reference

Hox genes and vertebrate axial pattern

31 March 2020

1 reference

HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4

31 March 2020

1 reference

Hoxb13 is required for normal differentiation and secretory function of the ventral prostate

31 March 2020

1 reference

The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer

31 March 2020

1 reference

Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1

31 March 2020

1 reference

HOXC6 and HOXC11 increase transcription of S100beta gene in BrdU-induced in vitro differentiation of GOTO neuroblastoma cells into Schwannian cells

31 March 2020

1 reference

HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition

31 March 2020

1 reference

HOXB13 promotes ovarian cancer progression

31 March 2020

1 reference

HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition

31 March 2020

1 reference

Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion.

31 March 2020

1 reference

Deregulated homeobox gene expression in cancer: cause or consequence?

31 March 2020

1 reference

Methylation of HoxA5 and HoxB5 and its relevance to expression during mouse development.

31 March 2020

1 reference

Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay

31 March 2020

1 reference

The trithorax group and Pc group proteins are differentially involved in heterochromatin formation in Drosophila

31 March 2020

1 reference

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

31 March 2020

1 reference

MLL translocations, histone modifications and leukaemia stem-cell development

31 March 2020

1 reference

Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation

31 March 2020

1 reference

MLL-rearranged leukemias: insights from gene expression profiling

31 March 2020

1 reference

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

31 March 2020

1 reference

HOXA9 is required for survival in human MLL-rearranged acute leukemias

31 March 2020

1 reference

MicroRNAs in the Hox network: an apparent link to posterior prevalence

31 March 2020

1 reference

"Mir"acles in hox gene regulation

31 March 2020

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A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands

31 March 2020

1 reference

Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer

31 March 2020

1 reference

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

31 March 2020

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Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster

31 March 2020

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Coordinated expression of ncRNAs and HOX mRNAs in the human HOXA locus

31 March 2020

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

31 March 2020

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

31 March 2020

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HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation

31 March 2020

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The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells

31 March 2020

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Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in viv

31 March 2020

1 reference

MEIS and PBX homeobox proteins in ovarian cancer.

31 March 2020

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Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

31 March 2020

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Homeobox genes in hematopoiesis and leukemogenesis

31 March 2020

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PBX proteins: much more than Hox cofactors

31 March 2020

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Hemangiomas and homeobox gene expression

31 March 2020

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Homeobox B3 promotes capillary morphogenesis and angiogenesis

31 March 2020

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Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes

31 March 2020

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Hoxb13 regulatory elements mediate transgene expression during prostate organogenesis and carcinogenesis

31 March 2020

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Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9.

31 March 2020

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Differential regulation of HOXA9 expression by nuclear factor kappa B (NF-kappaB) and HOXA9.

31 March 2020

1 reference

Neuroblastoma: biology, prognosis, and treatment

31 March 2020

1 reference

Adenosine receptors linked to adenylate cyclase activity in human neuroblastoma cells: modulation during cell differentiation

31 March 2020

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Differential expression of N-myc and c-src proto-oncogenes during neuronal and schwannian differentiation of human neuroblastoma cells

31 March 2020

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Up-regulation of HOXC6, HOXD1, and HOXD8 homeobox gene expression in human neuroblastoma cells following chemical induction of differentiation

31 March 2020

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HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling

31 March 2020

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Overexpression of the homeobox gene HOXC8 in human prostate cancer correlates with loss of tumor differentiation

31 March 2020

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PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation

31 March 2020

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Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract

31 March 2020

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The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?

31 March 2020

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The role of HOX homeobox genes in normal and leukemic hematopoiesis

31 March 2020

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

31 March 2020

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

31 March 2020

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A role for the HOXB7 homeodomain protein in DNA repair

31 March 2020

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Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis

31 March 2020

1 reference

Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway

31 March 2020

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A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

31 March 2020

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Exploring the two-gene ratio in breast cancer--independent roles for HOXB13 and IL17BR in prediction of clinical outcome

31 March 2020

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Gene expression profiles of human breast cancer progression

31 March 2020

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Compromised HOXA5 function can limit p53 expression in human breast tumours

31 March 2020

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HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8

31 March 2020

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Influence of Hoxa5 on p53 tumorigenic outcome in mice

31 March 2020

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HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer).

31 March 2020

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Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma.

31 March 2020

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

31 March 2020

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Hox genes in hematopoiesis and leukemogenesis.

31 March 2020

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HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis

31 March 2020

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HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia

31 March 2020

1 reference

Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model

31 March 2020

1 reference

Endocrine regulation of HOX genes

31 March 2020

1 reference

Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

31 March 2020

1 reference

Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth

31 March 2020

1 reference

Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation

31 March 2020

1 reference

Abdominal-A mediated repression of Cyclin E expression during cell-fate specification in the Drosophila central nervous system.

31 March 2020

1 reference

Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration.

31 March 2020

1 reference

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

31 March 2020

1 reference

HER-2, notch, and breast cancer stem cells: targeting an axis of evil

31 March 2020

1 reference

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

31 March 2020

1 reference

A tumorigenic homeobox (HOX) gene expressing human gastric cell line derived from putative gastric stem cell

31 March 2020

1 reference

Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes

31 March 2020

1 reference

Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

31 March 2020

1 reference

Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients.

31 March 2020

1 reference

A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen

31 March 2020

1 reference

HOXB13-to-IL17BR expression ratio is related with tumor aggressiveness and response to tamoxifen of recurrent breast cancer: a retrospective study

31 March 2020

1 reference

Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.

31 March 2020

1 reference

Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

31 March 2020

1 reference

Position-specific expression of Hox genes along the gastrointestinal tract

31 March 2020

1 reference

Aberrant cell adhesion molecule expression in human bronchopulmonary sequestration and congenital cystic adenomatoid malformation

31 March 2020

1 reference

Limb malformations and the human HOX genes

31 March 2020

1 reference

Transcriptional control of lung morphogenesis

31 March 2020

1 reference

Hox genes: from leukemia to hematopoietic stem cell expansion.

31 March 2020

1 reference

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

31 March 2020

1 reference

Hox homeobox genes as regulators of normal and leukemic hematopoiesis

31 March 2020

1 reference

Induced pluripotent stem cell lines derived from human somatic cells

31 March 2020

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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

31 March 2020

1 reference

Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.

31 March 2020

1 reference

Hoxb1 controls cell fate specification and proliferative capacity of neural stem and progenitor cells.

31 March 2020

1 reference

Hox regulation of normal and leukemic hematopoietic stem cells.

31 March 2020

1 reference

The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

31 March 2020

1 reference

Pbx1 is required for Hox D3-mediated angiogenesis

31 March 2020

1 reference

HOXB6 protein is bound to CREB-binding protein and represses globin expression in a DNA binding-dependent, PBX interaction-independent process

31 March 2020

1 reference

Smads oppose Hox transcriptional activities

31 March 2020

1 reference

HOXC5 and HOXC8 expression are selectively turned on in human cervical cancer cells compared to normal keratinocytes.

31 March 2020

1 reference

Pseudoallelism and gene evolution

31 March 2020

1 reference

A gene complex controlling segmentation in Drosophila

31 March 2020

1 reference

The molecular organization of the Antennapedia locus of Drosophila

31 March 2020

1 reference

Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila.

31 March 2020

1 reference

Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus

31 March 2020

1 reference

New murine homeoboxes: structure, chromosomal assignment, and differential expression in adult erythropoiesis

31 March 2020

1 reference

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

31 March 2020

1 reference

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

31 March 2020

1 reference

MicroRNA-directed cleavage of HOXB8 mRNA

31 March 2020

1 reference

Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages

31 March 2020

1 reference

12 December 2020

Homeobox genes in normal hematopoiesis and leukemia

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12 December 2020

Transcription factors and pattern formation in the developing lung

1 reference

12 December 2020

Aberrant HOXC expression accompanies the malignant phenotype in human prostate

1 reference

12 December 2020

Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.

1 reference

12 December 2020

Biological and therapeutic aspects of infant leukemia

1 reference

12 December 2020

Expression of HOXC4, HOXC5, and HOXC6 in human lymphoid cell lines, leukemias, and benign and malignant lymphoid tissue.

1 reference

12 December 2020

A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus

1 reference

12 December 2020

Disordered expression of HOX genes in human non-small cell lung cancer.

1 reference

12 December 2020

DNA methylation regulates MicroRNA expression

1 reference

12 December 2020

Cytogenetic Analysis of Chromosome 3 in DROSOPHILA MELANOGASTER: The Homoeotic Gene Complex in Polytene Chromosome Interval 84a-B.

1 reference

12 December 2020

Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma

1 reference

12 December 2020

Hox genes and the morphogenesis of the vertebrate limb.

1 reference

12 December 2020

Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity

1 reference

12 December 2020

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2826

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20357775%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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