The pathology of hepatic iron overload: a free radical--mediated process? (Q37870467)

24 August 2017

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title

The pathology of hepatic iron overload: a free radical--mediated process? (English)

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24 August 2017

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Bacon BR

1

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24 August 2017

Britton RS

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

1 January 1990

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24 August 2017

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24 August 2017

volume

11

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24 August 2017

issue

1

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24 August 2017

page(s)

127-137

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Hereditary hemochromatosis. Analysis of laboratory expression of the disease by genotype in 18 pedigrees

24 August 2017

cites work

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Biochemical changes in the tissues of animals injected with iron. 3. Lipid peroxidation

21 January 2018

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Effects of hexachlorobenzene feeding and iron overload on enzymes of haem biosynthesis and cytochrome P 450 in rat liver

21 January 2018

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Iron and the liver Acute and long-term effects of iron-loading on hepatic haem metabolism

21 January 2018

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Control of delta-aminolaevulinate synthase and haem oxygenase in chronic-iron-overloaded rats

21 January 2018

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Iron-induced DNA damage and synthesis in isolated rat liver nuclei

21 January 2018

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The role of iron in ferritin- and haemosiderin-mediated lipid peroxidation in liposomes.

21 January 2018

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Formation of hydroxyl radicals in the presence of ferritin and haemosiderin. Is haemosiderin formation a biological protective mechanism?

21 January 2018

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

Mechanisms of lipid peroxide formation in animal tissues

21 January 2018

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

Effect of ferritin-containing fractions with different iron loading on lipid peroxidation

21 January 2018

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

Effects of lipid peroxidation on membrane-bound enzymes of the endoplasmic reticulum

21 January 2018

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

Idiopathic hemochromatosis. Demonstration of recessive transmission and early detection by family HLA typing

21 January 2018

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7 January 2021

Idiopathic hemochromatosis: demonstration of homozygous-heterozygous mating by HLA typing of families

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7 January 2021

Prevalence of iron overload in central Sweden

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron overload: causes and consequences

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis

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7 January 2021

Prevalence of Hemochromatosis among 11,065 Presumably Healthy Blood Donors

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Role of the liver in normal iron metabolism

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron transport and storage

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron Overload Disorders: Natural History, Pathogenesis, Diagnosis, and Therapy

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Genetic hemochromatosis

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hereditary haemochromatosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Familial hemochromatosis. Physiologic studies in the precirrhotic stage of the disease

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Early detection of idiopathic haemochromatosis: relative value of serum-ferritin and HLA typing

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hepatocellular carcinoma in primary haemochromatosis in the absence of cirrhosis

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Siderosis in the bantu. A comparison of incidence in males and females

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https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Long-term Chelation Therapy in Thalassaemia Major: Effect on Liver Iron Concentration, Liver Histology, and Clinical Progress

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Transfusional iron overload: The relationship between tissue iron concentration and hepatic fibrosis in thalassaemia

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation and associated hepatic organelle dysfunction in iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Further Studies on Lipid-Peroxide Formation in Isolated Hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

The Consequences of Lipid Peroxidation in Isolated Hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Biochemical evidence for chemical and/or topographic differences in the lipoperoxidative processes induced by CCl4 and iron

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation in isolated rat hepatocytes: relationship to toxicity of CCl4, ADP/Fe3+, and diethyl maleate

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Comparison of the effects of metals on cellular injury and lipid peroxidation in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation stimulated by iron nitrilotriacetate in rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hepatic injury in chronic iron overload. Role of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

The Susceptibility to Autoxidation of Human Red Cell Lipids in Health and Disease

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Serum vitamin E levels with beta-thalassaemia major: preliminary report

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation in iron-overloaded spleens

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Chemical methods for the detection of lipid hydroperoxides

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Monitoring lipid peroxidation by breath analysis: endogenous hydrocarbons and their metabolic elimination

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Quantitative evaluation of ethane and n-pentane as indicators of lipid peroxidation in vivo

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Volatile hydrocarbon and carbonyl products of lipid peroxidation: A comparison of pentane, ethane, hexanal, and acetone as in vivo indices

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Effect of antioxidants on lipid peroxidation in iron-loaded rats

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

The importance of free radicals and catalytic metal ions in human diseases

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Autoxidation of polyunsaturated fatty acids: II. A suggested mechanism for the formation of TBA‐reactive materials from prostaglandin‐like endoperoxides

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Levels of malondialdehyde production in rat liver following loading and unloading with iron

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hepatic mitochondrial malondialdehyde metabolism in rats with chronic iron overload.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Microsomal lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Mechanisms and consequences of lipid peroxidation in biological systems

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Spectrophotometric detection of lipid conjugated dienes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Early onset of lipoperoxidation in rat liver after carbon tetrachloride administration.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hepatic lipid peroxidation in vivo in rats with chronic iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hepatic microsomal function in rats with chronic dietary iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Studies on the concentration and intracellular localization of iron proteins in liver biopsy specimens from patients with iron overload with special reference to their role in lysosomal disruption.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Acid Hydrolase Activities and Lysosomal Integrity in Liver Biopsies from Patients with Iron Overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron overload and lysosomal stability in beta zero-thalassaemia intermedia and trait: correlation between serum ferritin and serum N-acetyl-beta-D-glucosaminidase levels

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Activities of some free-radical scavenging enzymes and glutathione concentrations in human and rat liver and their relationship to the pathogenesis of tissue damage in iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Isolation of two lysosomal populations from iron-overloaded rat liver with different iron concentration and proteolytic activity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron-dependent loss of liver cytochrome P-450 haem in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Hemoprotein catabolism during stimulation of microsomal lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation and the degradation of cytochrome P-450 heme

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Properties of liver mitochondria from iron-loaded rats

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Effects of hexachlorobenzene and iron loading on rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Functional efficiency of mitochondrial membrane of rats with hepatic chronic iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Vitamin E and selenium protection from in vivo lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Effects of vitamin E deficiency on hepatic mitochondrial lipid peroxidation and oxidative metabolism in rats with chronic dietary iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Evidence for mitochondrial DNA damage by lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Experimental siderosis and liver injury in the rhesus monkey

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Experimental hepatic cirrhosis in dogs caused by chronic massive iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Experimental hepatic iron overload in the baboon: results of a two-year study. Evolution of biological and morphologic hepatic parameters of iron overload.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Chronic liver iron overload in the baboon by ferric nitrilotriacetate

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Pathogenesis of hepatic fibrosis in experimental iron overload

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Ferritin, a physiological iron donor for microsomal lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

A method for measurement of liver iron fractions in needle biopsy specimens and some results in acute liver disease

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Non-ferritin, non-heme iron pools in rat tissues

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

The role of lipid peroxidation in the induction of cation transport in rat liver mitochondria. The antioxidant effect of oligomycin and dicyclohexylcarbodiimide

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

The effect of ferric iron complex on Ca2+ transport in isolated rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Iron-induced peroxidative injury to isolated rat hepatic mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Lipid peroxidation of rat-liver microsomes. Its effect on the microsomal membrane and some membrane-bound microsomal enzymes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Destruction of liver microsomal calcium pump activity by carbon tetrachloride and bromotrichloromethane

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Carbon tetrachloride and bromotrichloromethane toxicity. Dual role of covalent binding of metabolic cleavage products and lipid peroxidation in depression of microsomal calcium sequestration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840110122

7 January 2021

Identifiers

DOI

10.1002/HEP.1840110122

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24 August 2017

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