MicroRNAs in neurodegenerative diseases and their therapeutic potential. (Q37946984)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

MicroRNAs in neurodegenerative diseases and their therapeutic potential (English)

1 reference

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14 January 2020

1 reference

1 reference

2

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14 January 2020

author name string

Eunsung Junn

series ordinal

1

1 reference

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14 January 2020

publication date

8 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology & Therapeutics

14 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

133

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

2

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14 January 2020

page(s)

142-150

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Neuronal type-specific gene expression profiling and laser-capture microdissection

14 January 2020

cites work

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Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter.

6 September 2017

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Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

6 September 2017

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MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice

6 September 2017

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miRNA malfunction causes spinal motor neuron disease

6 September 2017

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FGF20 rs12720208 SNP and microRNA-433 variation: no association with Parkinson's disease in Spanish patients.

6 September 2017

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MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study

6 September 2017

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MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons

6 September 2017

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Molecular diversity through RNA editing: a balancing act.

6 September 2017

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MicroRNAs and deregulated gene expression networks in neurodegeneration

6 September 2017

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MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases

6 September 2017

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Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation

6 September 2017

1 reference

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Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153

6 September 2017

1 reference

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Understanding microRNAs in neurodegeneration

6 September 2017

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Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains

6 September 2017

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The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

6 September 2017

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Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system

6 September 2017

1 reference

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Repression of alpha-synuclein expression and toxicity by microRNA-7.

6 September 2017

1 reference

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

6 September 2017

1 reference

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

6 September 2017

1 reference

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MicroRNAs: target recognition and regulatory functions

6 September 2017

1 reference

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FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression

6 September 2017

1 reference

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The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

6 September 2017

1 reference

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A miRNA signature of prion induced neurodegeneration

6 September 2017

1 reference

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The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

6 September 2017

1 reference

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MicroRNA target site polymorphisms and human disease

6 September 2017

1 reference

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miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis

6 September 2017

1 reference

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Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia

6 September 2017

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Mechanisms of neurodegeneration in Huntington's disease.

6 September 2017

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MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths

6 September 2017

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Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

6 September 2017

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

6 September 2017

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Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus

6 September 2017

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Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

6 September 2017

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

6 September 2017

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Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

6 September 2017

1 reference

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The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

6 September 2017

1 reference

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A MicroRNA feedback circuit in midbrain dopamine neurons

6 September 2017

1 reference

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MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

6 September 2017

1 reference

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Transvascular delivery of small interfering RNA to the central nervous system.

6 September 2017

1 reference

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MicroRNA gets down to business

6 September 2017

1 reference

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Interfering with disease: a progress report on siRNA-based therapeutics

6 September 2017

1 reference

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

6 September 2017

1 reference

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MicroRNA-133 controls cardiac hypertrophy

6 September 2017

1 reference

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Trinucleotide Repeat Disorders

6 September 2017

1 reference

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Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology

6 September 2017

1 reference

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RNAi therapeutics: a potential new class of pharmaceutical drugs

6 September 2017

1 reference

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

6 September 2017

1 reference

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

6 September 2017

1 reference

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Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

6 September 2017

1 reference

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

6 September 2017

1 reference

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

6 September 2017

1 reference

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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

6 September 2017

1 reference

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Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.

6 September 2017

1 reference

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

6 September 2017

1 reference

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The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

6 September 2017

1 reference

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A role for the P-body component GW182 in microRNA function

6 September 2017

1 reference

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A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Silencing of microRNAs in vivo with 'antagomirs'

6 September 2017

1 reference

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair

6 September 2017

1 reference

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

6 September 2017

1 reference

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA genes are transcribed by RNA polymerase II

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Dicer is essential for formation of the heterochromatin structure in vertebrate cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Unraveling the mechanisms involved in motor neuron degeneration in ALS

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Cytoplasmic foci are sites of mRNA decay in human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Sequence-specific inhibition of small RNA function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNAs: genomics, biogenesis, mechanism, and function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

alpha-Synuclein locus triplication causes Parkinson's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Introduction to the transmissible spongiform encephalopathies or prion diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

The nuclear RNase III Drosha initiates microRNA processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNAs and other tiny endogenous RNAs in C. elegans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Preferential neurotrophic activity of fibroblast growth factor‐20 for dopaminergic neurons through fibroblast growth factor receptor‐1c

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Pitx3 is required for development of substantia nigra dopaminergic neurons.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

A microRNA in a multiple-turnover RNAi enzyme complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

An extensive class of small RNAs in Caenorhabditis elegans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Structural clues to prion replication

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Antagomirzymes: oligonucleotide enzymes that specifically silence microRNA function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Stable knockdown of microRNA in vivo by lentiviral vectors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Small RNAs: delivering the future

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Gene dosage of the amyloid beta precursor protein in Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNAs can regulate human APP levels.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

APP and BACE1 miRNA genetic variability has no major role in risk for Alzheimer disease.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

A microRNA-based gene dysregulation pathway in Huntington's disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

MicroRNA pathways modulate polyglutamine-induced neurodegeneration.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

LNA-modified oligonucleotides mediate specific inhibition of microRNA function.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268953

10.1016/J.PHARMTHERA.2011.10.002

1 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22008259%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

22008259

1 reference