Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification (Q38034629)

27 August 2017

title

Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification (English)

1 reference

27 August 2017

author name string

Christopher W Brownlee

series ordinal

1

1 reference

27 August 2017

Gregory C Rogers

series ordinal

2

1 reference

27 August 2017

publication date

15 August 2012

1 reference

Cellular and Molecular Life Sciences

27 August 2017

published in

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27 August 2017

volume

70

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27 August 2017

issue

6

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27 August 2017

page(s)

1021-1034

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Centrioles: some self-assembly required.

27 August 2017

cites work

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Bld10p constitutes the cartwheel-spoke tip and stabilizes the 9-fold symmetry of the centriole

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Centriolar SAS-5 is required for centrosome duplication in C. elegans

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates

21 January 2018

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Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

21 January 2018

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21 January 2018

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The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.

21 January 2018

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The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.

21 January 2018

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21 January 2018

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The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification

21 January 2018

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Sequential protein recruitment in C. elegans centriole formation

21 January 2018

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21 January 2018

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The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication

21 January 2018

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Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication

21 January 2018

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Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila

21 January 2018

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Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome

21 January 2018

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Asterless is a scaffold for the onset of centriole assembly

21 January 2018

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Cep152 interacts with Plk4 and is required for centriole duplication.

21 January 2018

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Determination of the Plk4/Sak consensus phosphorylation motif using peptide spots arrays

21 January 2018

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Autophosphorylation of polo-like kinase 4 and its role in centriole duplication

21 January 2018

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Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

21 January 2018

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Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation

21 January 2018

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The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization

21 January 2018

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Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors

21 January 2018

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21 January 2018

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Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation

21 January 2018

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PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

21 January 2018

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The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

21 January 2018

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Cell-cycle-regulated expression of STIL controls centriole number in human cells

21 January 2018

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STIL is required for centriole duplication in human cells

21 January 2018

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Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium

21 January 2018

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21 January 2018

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Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells

21 January 2018

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Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance

21 January 2018

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A primary microcephaly protein complex forms a ring around parental centrioles.

21 January 2018

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21 January 2018

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The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

21 January 2018

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

21 January 2018

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Drosophila skpA, a component of SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation

21 January 2018

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Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication

21 January 2018

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Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase

21 January 2018

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BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number

21 January 2018

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Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis

21 January 2018

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Abnormal centrosome amplification in the absence of p53.

21 January 2018

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

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Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

21 January 2018

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Genotoxic stress leads to centrosome amplification in breast cancer cell lines that have an inactive G1/S cell cycle checkpoint

21 January 2018

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SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing

21 January 2018

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Metabolic control of G1-S transition: cyclin E degradation by p53-induced activation of the ubiquitin-proteasome system

21 January 2018

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Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

21 January 2018

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Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication

21 January 2018

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Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects

21 January 2018

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Anomalous centriole configurations are detected in Drosophila wing disc cells upon Cdk1 inactivation

21 January 2018

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Centrosomal amplification and spindle multipolarity in cancer cells

21 January 2018

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Structural Basis of PP2A Inhibition by Small t Antigen

21 January 2018

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Involvement of PP2A in viral and cellular transformation

21 January 2018

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Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40

21 January 2018

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PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen

21 January 2018

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Centrosome abnormalities during a Chlamydia trachomatis infection are caused by dysregulation of the normal duplication pathway

21 January 2018

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The DNA damage response to non-replicating adeno-associated virus: Centriole overduplication and mitotic catastrophe independent of the spindle checkpoint.

21 January 2018

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The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

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21 January 2018

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Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells

21 January 2018

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Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis

21 January 2018

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

21 January 2018

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The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression

21 January 2018

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Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A

21 January 2018

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The Polo kinase Plk4 functions in centriole duplication

21 January 2018

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12 December 2020

SAK/PLK4 is required for centriole duplication and flagella development

1 reference

12 December 2020

SAS-6 is a cartwheel protein that establishes the 9-fold symmetry of the centriole

1 reference

12 December 2020

E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner.

1 reference

12 December 2020

Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas

1 reference

12 December 2020

Mitotic aberration coupled with centrosome amplification is induced by hepatitis B virus X oncoprotein via the Ras-mitogen-activated protein/extracellular signal-regulated kinase-mitogen-activated protein pathway.

1 reference

12 December 2020

Microtubule organization during the early development of the parthenogenetic egg of the hymenopteran Muscidifurax uniraptor.

1 reference

12 December 2020

Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts

1 reference

12 December 2020

p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells

1 reference

12 December 2020

Control of daughter centriole formation by the pericentriolar material

1 reference

12 December 2020

Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication

1 reference

12 December 2020

Inhibition of BRCA1 in breast cell lines causes the centrosome duplication cycle to be disconnected from the cell cycle

1 reference

12 December 2020

Origin and maturation of centrioles in association with the nuclear envelope in hypertonic-stressed sea urchin eggs

1 reference

12 December 2020

Centrosome duplication: of rules and licenses

1 reference

12 December 2020

Right place, right time, and only once: replication initiation in metazoans

1 reference

12 December 2020

Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

1 reference

12 December 2020

Orc1 controls centriole and centrosome copy number in human cells

1 reference

12 December 2020

An investigation of the centriole cycle using 3T3 and CHO cells

1 reference

12 December 2020

10.1007/S00018-012-1102-6

Identifiers

DOI

1 reference

27 August 2017

1 reference