Parental imprinting regulates insulin-like growth factor signaling: a Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis (Q38058419)

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scientific article published on 8 November 2012

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English	Parental imprinting regulates insulin-like growth factor signaling: a Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis	scientific article published on 8 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

Parental imprinting regulates insulin-like growth factor signaling: a Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis (English)

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

Gabriela Schneider

object named as

G Schneider

3

0 references

Magdalena Kucia

object named as

M Kucia

5

0 references

Mariusz Ratajczak

1

object named as

M Z Ratajczak

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

author name string

D-M Shin

2

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

J Ratajczak

4

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

publication date

8 November 2012

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

27

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

773-779

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts

1 reference

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6 September 2017

Very small embryonic/epiblast-like stem cells (VSELs) and their potential role in aging and organ rejuvenation--an update and comparison to other primitive small stem cells isolated from adult tissues.

1 reference

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6 September 2017

The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs).

1 reference

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6 September 2017

Global gene expression analysis of very small embryonic-like stem cells reveals that the Ezh2-dependent bivalent domain mechanism contributes to their pluripotent state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

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Downregulation of H19 improves the differentiation potential of mouse parthenogenetic embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Reduced number of VSELs in the bone marrow of growth hormone transgenic mice indicates that chronically elevated Igf1 level accelerates age-dependent exhaustion of pluripotent stem cell pool: a novel view on aging

1 reference

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6 September 2017

Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells

1 reference

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6 September 2017

The role of pluripotent embryonic-like stem cells residing in adult tissues in regeneration and longevity

1 reference

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6 September 2017

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

1 reference

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6 September 2017

Higher number of stem cells in the bone marrow of circulating low Igf-1 level Laron dwarf mice--novel view on Igf-1, stem cells and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

The growth hormone receptor: mechanism of activation and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

The proliferating role of insulin and insulin-like growth factors in cancer

1 reference

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6 September 2017

Epiblast/germ line hypothesis of cancer development revisited: lesson from the presence of Oct-4+ cells in adult tissues

1 reference

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6 September 2017

Nuclear and chromatin reorganization during cell senescence and aging - a mini-review

1 reference

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6 September 2017

Insulin signaling and life span.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Very small embryonic/epiblast-like stem cells: a missing link to support the germ line hypothesis of cancer development?

1 reference

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6 September 2017

Very small embryonic-like stem cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Insulin and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: physiology and pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Identification of very small embryonic like (VSEL) stem cells in bone marrow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Endocrine regulation of ageing

1 reference

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6 September 2017

Phenotypic plasticity and the epigenetics of human disease

1 reference

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6 September 2017

Germ cell specification in mice

1 reference

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6 September 2017

A hypothesis for an embryonic origin of pluripotent Oct-4(+) stem cells in adult bone marrow and other tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Genetic and epigenetic regulators of pluripotency

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The imprinted H19 noncoding RNA is a primary microRNA precursor

1 reference

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A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow

1 reference

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6 September 2017

A census of mammalian imprinting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Life extension in the dwarf mouse

1 reference

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6 September 2017

Epigenetic regulation of mammalian genomic imprinting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

6 September 2017

Birth of parthenogenetic mice that can develop to adulthood

1 reference

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6 September 2017

CTCF maintains differential methylation at the Igf2/H19 locus

1 reference

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6 September 2017

Genomic imprinting: parental influence on the genome

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H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.

1 reference

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Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.

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Derivation of pluripotent stem cells from cultured human primordial germ cells

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Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

1 reference

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Disruption of imprinting caused by deletion of the H19 gene region in mice

1 reference

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Molecular signature of adult bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin

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Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway

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Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction

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Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke

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Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

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31 August 2018

Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report.

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31 August 2018

Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression

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31 August 2018

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31 August 2018

Loss of imprinting of human insulin-like growth factor II gene, IGF2, in acute myeloid leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5538807

31 August 2018

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

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31 August 2018

The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion

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Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression

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21 January 2018

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Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects.

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A Loss of Insulin-like Growth Factor-2 Imprinting Is Modulated by CCCTC-binding Factor Down-regulation at Senescence in Human Epithelial Cells

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A human H19 transgene exhibits impaired paternal-specific imprint acquisition and maintenance in mice

1 reference

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Bisulfite sequencing and dinucleotide content analysis of 15 imprinted mouse differentially methylated regions (DMRs): paternally methylated DMRs contain less CpGs than maternally methylated DMRs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23135355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/23135355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin-like growth factor system in normal and malignant hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23135355

12 December 2020

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/23135355

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Growth Defect Blocks Cancer and Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23135355

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Mono- and bi-allelic expression of insulin-like growth factor II gene in human muscle tumors

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12 December 2020

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Identifiers

10.1038/LEU.2012.322

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 August 2017

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