The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics (Q38197846)

30 August 2017

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title

The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics (English)

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30 August 2017

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Claire E Eyers

4

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author name string

Francesco Lanucara

series ordinal

1

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30 August 2017

Stephen W Holman

series ordinal

2

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30 August 2017

Christopher J Gray

series ordinal

3

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30 August 2017

publication date

1 April 2014

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30 August 2017

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30 August 2017

volume

6

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30 August 2017

issue

4

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30 August 2017

page(s)

281-294

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Oxytocin-receptor binding: why divalent metals are essential

30 August 2017

cites work

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12 December 2020

Detection of a Protein Conformational Equilibrium by Electrospray Ionisation-Ion Mobility-Mass Spectrometry

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12 December 2020

High-resolution ion cyclotron mobility spectrometry

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12 December 2020

Conformation of polyalanine and polyglycine dications in the gas phase: insight from ion mobility spectrometry and replica-exchange molecular dynamics

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12 December 2020

Evidence for α-helices in the gas phase: a case study using Melittin from honey bee venom.

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12 December 2020

Improvement of phosphoproteome analyses using FAIMS and decision tree fragmentation. application to the insulin signaling pathway in Drosophila melanogaster S2 cells

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12 December 2020

Assessing the dynamic range and peak capacity of nanoflow LC-FAIMS-MS on an ion trap mass spectrometer for proteomics

1 reference

12 December 2020

A novel method for the determination of the site of glucuronidation by ion mobility spectrometry-mass spectrometry

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12 December 2020

Accelerated high-resolution differential ion mobility separations using hydrogen

1 reference

12 December 2020

Structural characterization of drug-like compounds by ion mobility mass spectrometry: comparison of theoretical and experimentally derived nitrogen collision cross sections

1 reference

12 December 2020

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

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12 December 2020

Effects of traveling wave ion mobility separation on data independent acquisition in proteomics studies

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12 December 2020

On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

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12 December 2020

Amphipathic polymers enable the study of functional membrane proteins in the gas phase

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12 December 2020

The effect of calcium ions and peptide ligands on the relative stabilities of the calmodulin dumbbell and compact structures

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12 December 2020

The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation

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12 December 2020

Product ion mobility as a promising tool for assignment of positional isomers of drug metabolites

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12 December 2020

Native ion mobility-mass spectrometry and related methods in structural biology

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12 December 2020

The 'sticky business' of cleaning gas-phase membrane proteins: a detergent oriented perspective

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12 December 2020

The extent and effects of peptide sequence scrambling via formation of macrocyclic B ions in model proteins.

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12 December 2020

Desorption electrospray ionization mass spectrometric analysis of organophosphorus chemical warfare agents using ion mobility and tandem mass spectrometry

1 reference

12 December 2020

Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics

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12 December 2020

Separation mechanism of chiral impurities, ephedrine and pseudoephedrine, found in amphetamine-type substances using achiral modifiers in the gas phase

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12 December 2020

Helices and Sheets in vacuo

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12 December 2020

Structure, stability and dynamics of norovirus P domain derived protein complexes studied by native mass spectrometry

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12 December 2020

Ultrasensitive identification of localization variants of modified peptides using ion mobility spectrometry

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12 December 2020

20S proteasomes have the potential to keep substrates in store for continual degradation

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12 December 2020

Monitoring copopulated conformational states during protein folding events using electrospray ionization-ion mobility spectrometry-mass spectrometry

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12 December 2020

Gas-phase conformations and folding energetics of oligonucleotides: dTG- and dGT-.

1 reference

12 December 2020

Mass spectrometry and the amyloid problem--how far can we go in the gas phase?

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12 December 2020

Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

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12 December 2020

Aβ(39-42) modulates Aβ oligomerization but not fibril formation

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12 December 2020

QconCAT Standard for Calibration of Ion Mobility-Mass Spectrometry Systems

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12 December 2020

Chaperonin complexes monitored by ion mobility mass spectrometry

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12 December 2020

How alkali metal ion binding alters the conformation preferences of gramicidin A: a molecular dynamics and ion mobility study

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12 December 2020

Conformational selection underlies recognition of a molybdoenzyme by its dedicated chaperone

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12 December 2020

DNA Hairpin, Pseudoknot, and Cruciform Stability in a Solvent-Free Environment

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12 December 2020

Evidence for macromolecular protein rings in the absence of bulk water.

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12 December 2020

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing.

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12 December 2020

Mass spectrometry methods for intrinsically disordered proteins.

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12 December 2020

Ion mobility spectrometry-mass spectrometry performance using electrodynamic ion funnels and elevated drift gas pressures

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12 December 2020

An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry

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12 December 2020

Shapes of supramolecular cages by ion mobility mass spectrometry

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12 December 2020

Resolution of isomeric multi-ruthenated porphyrins by travelling wave ion mobility mass spectrometry

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12 December 2020

Electrospray ionization mass spectrometry and ion mobility analysis of the 20S proteasome complex

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12 December 2020

Tandem differential mobility analysis-mass spectrometry reveals partial gas-phase collapse of the GroEL complex

1 reference

12 December 2020

Direct evidence for the gas phase thermal polymerization of styrene. Determination of the initiation mechanism and structures of the early oligomers by ion mobility

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12 December 2020

Native protein MS and ion mobility large flying proteins with ESI.

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12 December 2020

Protonated arginine and protonated lysine: hydration and its effect on the stability of salt-bridge structures.

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12 December 2020

A novel differential mobility analyzer as a VOC detector and multivariate techniques for identification and quantification

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12 December 2020

Charge-State Dependent Compaction and Dissociation of Protein Complexes: Insights from Ion Mobility and Molecular Dynamics

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12 December 2020

Ion Mobility Mass Spectrometry of Peptide Ions: Effects of Drift Gas and Calibration Strategies

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12 December 2020

Identifying metabolite ions of peptide drugs in the presence of an in vivo matrix background

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12 December 2020

Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology

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12 December 2020

Effects of Drift Gas on Collision Cross Sections of a Protein Standard in Linear Drift Tube and Traveling Wave Ion Mobility Mass Spectrometry

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12 December 2020

Biomolecular folding in vacuo!!!(?)

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12 December 2020

Stability and shape of hepatitis B virus capsids in vacuo

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12 December 2020

Ammonium ion at low concentration stabilizes the G-quadruplex formation by telomeric sequence

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12 December 2020

Gas-phase unfolding and disassembly reveals stability differences in ligand-bound multiprotein complexes

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12 December 2020

Size, weight and position: ion mobility spectrometry and imaging MS combined.

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12 December 2020

Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

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12 December 2020

Ion mobility mass spectrometry for peptide analysis

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12 December 2020

Resolution of a paradox by native mass spectrometry: facile occupation of all four metal binding sites in the dimeric zinc sensor SmtB

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12 December 2020

Enhancements in travelling wave ion mobility resolution

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12 December 2020

Ion Mobility and Collision-Induced Dissociation Analysis of Carbonic Anhydrase 2

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12 December 2020

Shift reagents for multidimensional ion mobility spectrometry-mass spectrometry analysis of complex peptide mixtures: evaluation of 18-crown-6 ether complexes

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12 December 2020

Native mass spectrometry: a bridge between interactomics and structural biology

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12 December 2020

Structure and dynamics of oligomeric intermediates in β2-microglobulin self-assembly

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12 December 2020

Effects of ion/ion proton transfer reactions on conformation of gas-phase cytochrome c ions

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12 December 2020

Conformation types of ubiquitin [M+8H]8+ Ions from water:methanol solutions: evidence for the N and A States in aqueous solution

1 reference

12 December 2020

Enhanced sensitivity in proteomics experiments using FAIMS coupled with a hybrid linear ion trap/Orbitrap mass spectrometer.

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12 December 2020

Extracted Fragment Ion Mobility Distributions: A New Method for Complex Mixture Analysis

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12 December 2020

Spermine binding to Parkinson's protein alpha-synuclein and its disease-related A30P and A53T mutants

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12 December 2020

Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding

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12 December 2020

A Scanning Frequency Mode for Ion Cyclotron Mobility Spectrometry

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12 December 2020

Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry

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12 December 2020

Characterizing the resolution and accuracy of a second-generation traveling-wave ion mobility separator for biomolecular ions

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12 December 2020

Collision induced unfolding of protein ions in the gas phase studied by ion mobility-mass spectrometry: the effect of ligand binding on conformational stability

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12 December 2020

Exploring crown ethers as shift reagents for ion mobility spectrometry

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12 December 2020

Sites of metabolic substitution: investigating metabolite structures utilising ion mobility and molecular modelling

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12 December 2020

The use of shift reagents in ion mobility-mass spectrometry: studies on the complexation of an active pharmaceutical ingredient with polyethylene glycol excipients

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12 December 2020

Amyloid beta-protein monomer structure: a computational and experimental study.

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12 December 2020

Circular dichroism techniques: biomolecular and nanostructural analyses- a review.

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12 December 2020

The gas phase structure of coulombically stretched polyethylene glycol ions

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12 December 2020

Folding and unfolding of helix-turn-helix motifs in the gas phase

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12 December 2020

Assigning structures to gas-phase peptide cations and cation-radicals. An infrared multiphoton dissociation, ion mobility, electron transfer, and computational study of a histidine peptide ion.

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12 December 2020

Applications of a travelling wave-based radio-frequency-only stacked ring ion guide

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12 December 2020

Atmospheric pressure ion mobility spectrometry of protonated and sodiated peptides

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12 December 2020

Electrospray ionization high-field asymmetric waveform ion mobility spectrometry-mass spectrometry

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12 December 2020

On the dynamics of fragment isomerization in collision-induced dissociation of peptides

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12 December 2020

Hydration of gas-phase ions formed by electrospray ionization

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12 December 2020

Z-Phe-Ala-diazomethylketone (PADK) disrupts and remodels early oligomer states of the Alzheimer disease Aβ42 protein.

1 reference

12 December 2020

Structural stability from solution to the gas phase: native solution structure of ubiquitin survives analysis in a solvent-free ion mobility-mass spectrometry environment

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12 December 2020

Peptides and proteins in the vapor phase

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12 December 2020

Real-time 2D separation by LC × differential ion mobility hyphenated to mass spectrometry

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12 December 2020

Native protein mass spectrometry: from intact oligomers to functional machineries.

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12 December 2020

Structural Preferences of Gas-Phase M2TMP Monomers upon Sequence Variations

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12 December 2020

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase

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12 December 2020

Proposal for a common nomenclature for peptide fragment ions generated following sequence scrambling during collision-induced dissociation

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12 December 2020

Separation and characterization of metallosupramolecular libraries by ion mobility mass spectrometry

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12 December 2020

Non‐covalent interactions of alkali metal cations with singly charged tryptic peptides

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12 December 2020

Do Charge State Signatures Guarantee Protein Conformations?

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12 December 2020

Identification and subsequent removal of an interference by FAIMS in the bioanalysis of dianicline in animal plasma

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12 December 2020

Carbohydrate structure characterization by tandem ion mobility mass spectrometry (IMMS)2.

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12 December 2020

Aspects of native proteins are retained in vacuum.

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12 December 2020

Using a Buffer Gas Modifier to Change Separation Selectivity in Ion Mobility Spectrometry

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12 December 2020

Factors contributing to the collision cross section of polyatomic ions in the kilodalton to gigadalton range: application to ion mobility measurements

1 reference

12 December 2020

Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy.

1 reference

12 December 2020

Design, synthesis, and traveling wave ion mobility mass spectrometry characterization of iron(II)- and ruthenium(II)-terpyridine metallomacrocycles

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12 December 2020

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion-molecule clustering reactions.

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12 December 2020

Stepwise evolution of protein native structure with electrospray into the gas phase, 10(-12) to 10(2) s

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12 December 2020

Separation and identification of isomeric glycopeptides by high field asymmetric waveform ion mobility spectrometry

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12 December 2020

High-resolution differential ion mobility separations using helium-rich gases

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12 December 2020

Conformation of macromolecules in the gas phase: use of matrix-assisted laser desorption methods in ion chromatography.

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12 December 2020

Factors that influence helical preferences for singly charged gas-phase peptide ions: the effects of multiple potential charge-carrying sites

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12 December 2020

Matthews coefficient probabilities: Improved estimates for unit cell contents of proteins, DNA, and protein-nucleic acid complex crystals

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12 December 2020

Ion trapping for ion mobility spectrometry measurements in a cyclical drift tube.

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12 December 2020

Rapid analysis of isomeric exogenous metabolites by differential mobility spectrometry-mass spectrometry

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12 December 2020

Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements.

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12 December 2020

Studies of peptide a- and b-type fragment ions using stable isotope labeling and integrated ion mobility/tandem mass spectrometry

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12 December 2020

Tetramolecular G-quadruplex formation pathways studied by electrospray mass spectrometry.

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12 December 2020

Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections

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12 December 2020

Application of FAIMS to anabolic androgenic steroids in sport drug testing

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12 December 2020

Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation

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12 December 2020

Size dependence of the folding of multiply charged sodium cationized polylactides revealed by ion mobility mass spectrometry and molecular modelling

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12 December 2020

Evidence for unfolding and refolding of gas-phase cytochrome C ions in a Paul trap

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12 December 2020

Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

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12 December 2020

Diastereomer assignment of an olefin-linked bis-paracyclophane by ion mobility mass spectrometry

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12 December 2020

Structure of triplex DNA in the gas phase

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12 December 2020

Structures of Metallosupramolecular Coordination Assemblies Can Be Obtained by Ion Mobility Spectrometry−Mass Spectrometry

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12 December 2020

Separation of protein conformers by differential ion mobility in hydrogen-rich gases

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12 December 2020

High-definition differential ion mobility spectrometry with resolving power up to 500

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12 December 2020

Water structure and interactions with protein surfaces

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12 December 2020

Drift Tube‐Mass Spectrometer for Studies of Low‐Energy Ion‐Molecule Reactions

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https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

Aerosol classification by electric mobility: apparatus, theory, and applications

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

A novel projection approximation algorithm for the fast and accurate computation of molecular collision cross sections (II). Model parameterization and definition of empirical shape factors for proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

The effect of salt on the conformations of three model proteins is revealed by variable temperature ion mobility mass spectrometry

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https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

G-quadruplexes in telomeric repeats are conserved in a solvent-free environment

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https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

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https://api.crossref.org/works/10.1038%2FNCHEM.1889

7 January 2021

Identifiers

DOI

10.1038/NCHEM.1889

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Dimensions Publication ID

30 August 2017

1020971442

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