Ntg2p, a Saccharomyces cerevisiae DNA N-glycosylase/apurinic or apyrimidinic lyase involved in base excision repair of oxidative DNA damage, interacts with the DNA mismatch repair protein Mlh1p. Identification of a Mlh1p binding motif. (Q38288690)

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English	Ntg2p, a Saccharomyces cerevisiae DNA N-glycosylase/apurinic or apyrimidinic lyase involved in base excision repair of oxidative DNA damage, interacts with the DNA mismatch repair protein Mlh1p. Identification of a Mlh1p binding motif.	scientific article

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12042306%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Ntg2p, a Saccharomyces cerevisiae DNA N-glycosylase/apurinic or apyrimidinic lyase involved in base excision repair of oxidative DNA damage, interacts with the DNA mismatch repair protein Mlh1p. Identification of a Mlh1p binding motif (English)

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9 November 2019

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Saccharomyces cerevisiae

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based on heuristic

inferred from title

DNA mismatch repair

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based on heuristic

inferred from title

1

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9 November 2019

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9 November 2019

author name string

Serge Boiteux

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31 May 2002

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9 November 2019

Journal of Biological Chemistry

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9 November 2019

277

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9 November 2019

33

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9 November 2019

29963-29972

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9 November 2019

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

1 reference

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Chemical determination of free radical-induced damage to DNA

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Studies on the catalytic mechanism of five DNA glycosylases. Probing for enzyme-DNA imino intermediates

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21 January 2018

DNA glycosylases

1 reference

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21 January 2018

The base excision repair pathway

1 reference

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21 January 2018

Repair of oxidized DNA bases in the yeast Saccharomyces cerevisiae

1 reference

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21 January 2018

Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli

1 reference

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Purification, characterization, gene cloning, and expression of Saccharomyces cerevisiae redoxyendonuclease, a homolog of Escherichia coli endonuclease III.

1 reference

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Substrate specificities of the ntg1 and ntg2 proteins of Saccharomyces cerevisiae for oxidized DNA bases are not identical

1 reference

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21 January 2018

The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast

1 reference

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21 January 2018

Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae

1 reference

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21 January 2018

Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

1 reference

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Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

1 reference

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21 January 2018

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

1 reference

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21 January 2018

Substrate specificity of the Ogg1 protein of Saccharomyces cerevisiae: excision of guanine lesions produced in DNA by ionizing radiation- or hydrogen peroxide/metal ion-generated free radicals

1 reference

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21 January 2018

Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae

1 reference

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21 January 2018

Alternative nucleotide incision repair pathway for oxidative DNA damage

1 reference

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21 January 2018

Inactivation of OGG1 increases the incidence of G . C-->T . A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells.

1 reference

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21 January 2018

Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway.

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The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiae

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21 January 2018

Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS).

1 reference

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21 January 2018

Induction of microsatellite instability by oxidative DNA damage

1 reference

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21 January 2018

Activation of human MutS homologs by 8-oxo-guanine DNA damage

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21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

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21 January 2018

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

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21 January 2018

Improved method for high efficiency transformation of intact yeast cells

1 reference

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21 January 2018

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

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21 January 2018

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

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21 January 2018

Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects

1 reference

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21 January 2018

Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae

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21 January 2018

Two rotameric forms of open ring 7-methylguanine are present in alkylated polynucleotides

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The distribution of the numbers of mutants in bacterial populations

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Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

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21 January 2018

Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction

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Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

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DNA mismatch repair and genetic instability

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High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer

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Eukaryotic DNA mismatch repair

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Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

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Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair

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Repair of 8-oxoguanine in Saccharomyces cerevisiae: interplay of DNA repair and replication mechanisms

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3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins

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Molecular matchmakers

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Identifiers

10.1074/JBC.M202963200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12042306%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12042306%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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