DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro (Q38290311)

1 September 2017

title

DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro (English)

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1 September 2017

Leigh A Henricksen

1

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1 September 2017

Janaki Veeraraghavan

series ordinal

2

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1 September 2017

David R Chafin

series ordinal

3

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1 September 2017

Robert A Bambara

series ordinal

4

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1 September 2017

language of work or name

English

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publication date

10 April 2002

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

277

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1 September 2017

issue

25

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1 September 2017

page(s)

22361-22369

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Demystified ... microsatellites

1 September 2017

cites work

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DNA repeat expansions and human disease

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Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability.

21 January 2018

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Stabilizing effects of interruptions on trinucleotide repeat expansions in Saccharomyces cerevisiae

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CTG repeats associated with human genetic disease are inherently flexible

21 January 2018

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Structural analysis of slipped-strand DNA (S-DNA) formed in (CTG)n. (CAG)n repeats from the myotonic dystrophy locus

21 January 2018

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Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases

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Triplet repeats form secondary structures that escape DNA repair in yeast

21 January 2018

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Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases

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Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice

21 January 2018

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Gender of the embryo contributes to CAG instability in transgenic mice containing a Huntington's disease gene

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Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome

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Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae

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CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae

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Enzymes and reactions at the eukaryotic DNA replication fork

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Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).

21 January 2018

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Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism

21 January 2018

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

21 January 2018

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Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats

21 January 2018

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The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

21 January 2018

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Trinucleotide repeats that expand in human disease form hairpin structures in vitro

21 January 2018

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Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast

21 January 2018

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Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex

21 January 2018

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Trinucleotide expansion in haploid germ cells by gap repair

21 January 2018

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The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

21 January 2018

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Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes

21 January 2018

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Repeat expansion--all in a flap?

21 January 2018

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A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

21 January 2018

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Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation

21 January 2018

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Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion

21 January 2018

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Gene conversion (recombination) mediates expansions of CTG[middle dot]CAG repeats

21 January 2018

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Expansion and length-dependent fragility of CTG repeats in yeast

21 January 2018

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Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

21 January 2018

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Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201765200

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1 September 2017

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