The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements (Q38302512)

1 September 2017

title

The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements (English)

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1 September 2017

8

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Albert T

1

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Wells J

2

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Funk JO

3

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Pullner A

4

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Raschke EE

5

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Stelzer G

6

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Meisterernst M

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1 September 2017

Eick D

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language of work or name

English

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publication date

20 February 2001

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Journal of Biological Chemistry

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published in

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volume

276

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1 September 2017

issue

23

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1 September 2017

page(s)

20482-20490

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ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1 September 2017

cites work

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The SWI/SNF complex creates loop domains in DNA and polynucleosome arrays and can disrupt DNA-histone contacts within these domains

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The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged.

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The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region

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Variable pause positions of RNA polymerase II lie proximal to the c-myc promoter irrespective of transcriptional activity.

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myc function and regulation

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MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination

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Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene

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The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter

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Both coding exons of the c-myc gene contribute to its posttranscriptional regulation in the quiescent liver and regenerating liver and after protein synthesis inhibition

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Nucleosomal structure of active and inactive c-myc genes

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Nucleosomal structures of c-myc promoters with transcriptionally engaged RNA polymerase II.

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Sequences in the human c-myc P2 promoter affect the elongation and premature termination of transcripts initiated from the upstream P1 promoter

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c-Myc target gene specificity is determined by a post-DNAbinding mechanism

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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MAZ, a Myc-associated zinc finger protein, is essential for the ME1a1-mediated expression of the c-myc gene during neuroectodermal differentiation of P19 cells.

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A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter

21 January 2018

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Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor

21 January 2018

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The human cut homeodomain protein represses transcription from the c-myc promoter

21 January 2018

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An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

21 January 2018

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Transcriptional repression by the insulator protein CTCF involves histone deacetylases

21 January 2018

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Repeated CT elements bound by zinc finger proteins control the absolute and relative activities of the two principal human c-myc promoters

21 January 2018

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Long-distance transcriptional enhancement by the histone acetyltransferase PCAF.

21 January 2018

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Histone deacetylase 1 can repress transcription by binding to Sp1.

21 January 2018

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Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

21 January 2018

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A single point mutation in TFIIA suppresses NC2 requirement in vivo

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M100265200

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1 September 2017

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