Architectural accommodation in the complex of four p53 DNA binding domain peptides with the p21/waf1/cip1 DNA response element (Q38345165)

2 September 2017

title

Architectural accommodation in the complex of four p53 DNA binding domain peptides with the p21/waf1/cip1 DNA response element (English)

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2 September 2017

8

Harrington RE

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author name string

Nagaich AK

1

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2 September 2017

Zhurkin VB

2

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2 September 2017

Sakamoto H

3

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2 September 2017

Gorin AA

4

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2 September 2017

Clore GM

5

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2 September 2017

Gronenborn AM

6

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2 September 2017

Appella E

7

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2 September 2017

language of work or name

English

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publication date

1 June 1997

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

272

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2 September 2017

issue

23

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2 September 2017

page(s)

14830-14841

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Cancer. p53, guardian of the genome

2 September 2017

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The tumor suppressor genes

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WAF1, a potential mediator of p53 tumor suppression

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The p53 proto-oncogene can act as a suppressor of transformation

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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p53: at the crossroads of molecular carcinogenesis and risk assessment

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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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p53 tagged sites from human genomic DNA.

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Definition of a consensus binding site for p53

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p53 mutations in human cancers

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA.

21 January 2018

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DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53.

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

21 January 2018

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Static and statistical bending of DNA evaluated by Monte Carlo simulations

21 January 2018

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Hydroxyl radical footprinting: a high-resolution method for mapping protein-DNA contacts

21 January 2018

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Crystal structure of CATGGCCATG and its implications for A-tract bending models

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Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees

21 January 2018

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1.9 A resolution refined structure of TBP recognizing the minor groove of TATAAAAG

21 January 2018

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18 DNA contacts probed by modification protection and interference studies

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Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

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Transition metal ion activation of DNA binding by the diphtheria tox repressor requires the formation of stable homodimers

21 January 2018

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Interaction of p53 with its consensus DNA-binding site

21 January 2018

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

21 January 2018

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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

21 January 2018

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Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

21 January 2018

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Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

21 January 2018

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Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

21 January 2018

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Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

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Discrimination of DNA Binding Sites by Mutant p53 Proteins

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Structural studies of protein-nucleic acid interaction: the sources of sequence-specific binding

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Sequence-dependent kinks induced in curved DNA.

21 January 2018

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Sequence periodicities in chicken nucleosome core DNA.

21 January 2018

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Curved DNA without A-A: experimental estimation of all 16 DNA wedge angles

21 January 2018

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Structural comparison between the d(CTAG) sequence in oligonucleotides and trp and met repressor-operator complexes

21 January 2018

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Crystal structure of trp repressor/operator complex at atomic resolution

21 January 2018

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Architectural transcription factors

21 January 2018

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21 January 2018

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Crystal structure of a TFIIB-TBP-TATA-element ternary complex

21 January 2018

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Allosteric activation of latent p53 tetramers

21 January 2018

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The missing nucleoside experiment: a new technique to study recognition of DNA by protein

21 January 2018

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21 January 2018

No room at the p53 inn

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New link found between p53 and DNA repair

21 January 2018

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

21 January 2018

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Hydroxyl radical footprinting

21 January 2018

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B-DNA twisting correlates with base-pair morphology.

21 January 2018

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Physiological concentration of magnesium ions induces a strong macroscopic curvature in GGGCCC-containing DNA

21 January 2018

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Bending and torsional flexibility of G/C-rich sequences as determined by cyclization assays

21 January 2018

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CAP binding sites reveal pyrimidine-purine pattern characteristic of DNA bending

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.23.14830

1 reference

2 September 2017

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