The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling (Q38349130)

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scientific article published on January 1997

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English	The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling	scientific article published on January 1997

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

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phosphorylation

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based on heuristic

inferred from title

9

object named as

Wiley HS

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2 September 2017

author name string

Huang HS

1

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Nagane M

2

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2 September 2017

Klingbeil CK

3

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2 September 2017

Lin H

4

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2 September 2017

Nishikawa R

5

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2 September 2017

Ji XD

6

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2 September 2017

Huang CM

7

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2 September 2017

Gill GN

8

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2 September 2017

Cavenee WK

10

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language of work or name

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publication date

1 January 1997

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2 September 2017

Journal of Biological Chemistry

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2 September 2017

272

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5

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2 September 2017

2927-2935

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Europe PubMed Central

PubMed publication ID

2 September 2017

describes a project that uses

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p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Amplification of Epidermal Growth Factor Receptor Gene in Gliomas: Histopathology and Prognosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Epidermal growth factor and transforming growth factor alpha bind differently to the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Factors affecting long-term stability of Moloney murine leukemia virus-based vectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Immunodetection of the Ligand-Activated Receptor for Epidermal Growth Factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Specific factors are required for kinase-dependent endocytosis of insulin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Autophosphorylation sites on the epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Analysis of substrate recognition determinants in a synthetic peptide containing the Tyr 1173 autophosphorylation site of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Signalling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Protein modules and signalling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Requirement for the adapter protein GRB2 in EGF receptor endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

HIV-1 evolution and disease progression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2927

21 January 2018

Identifiers

10.1074/JBC.272.5.2927

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

0 references

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