CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function. (Q38343937)

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scientific article published on 08 March 2004

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English	CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function.	scientific article published on 08 March 2004

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25 December 2019

CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function (English)

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25 December 2019

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Monika C Brunner-Weinzierl

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25 December 2019

Andreas Radbruch

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Andreas Radbruch

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25 December 2019

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Pushpa Pandiyan

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25 December 2019

Dagmar Gärtner

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25 December 2019

Osman Soezeri

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25 December 2019

Klaus Schulze-Osthoff

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25 December 2019

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8 March 2004

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25 December 2019

Journal of Experimental Medicine

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25 December 2019

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25 December 2019

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25 December 2019

831-842

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25 December 2019

Interferon gamma is required for activation-induced death of T lymphocytes

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6 September 2017

CTLA-4: new insights into its biological function and use in tumor immunotherapy

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6 September 2017

Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

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6 September 2017

IL-2 and related cytokines can promote T cell survival by activating AKT.

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6 September 2017

Lymphocyte apoptosis: refining the paths to perdition

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6 September 2017

Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells

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6 September 2017

CTLA-4 blockade of antigen-induced cell death

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6 September 2017

Apoptosis genes and autoimmunity.

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Cellular survival: a play in three Akts

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6 September 2017

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

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Apoptosis signaling in lymphocytes.

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6 September 2017

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

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6 September 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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6 September 2017

Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking

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6 September 2017

The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens

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6 September 2017

Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis

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6 September 2017

CTLA-4 ligation blocks CD28-dependent T cell activation

1 reference

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6 September 2017

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212725

6 September 2017

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

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6 September 2017

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

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6 September 2017

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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6 September 2017

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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6 September 2017

Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

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14 September 2017

Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases.

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27 September 2017

Expression and function of CTLA-4 in Th1 and Th2 cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212725

27 September 2017

Th1 and Th2 subsets equally undergo Fas-dependent and -independent activation-induced cell death

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212725

27 September 2017

The role of CTLA-4 in the regulation and initiation of T-cell responses

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27 September 2017

Cytotoxic T lymphocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function

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23 June 2018

Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression

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23 June 2018

CTLA-4-Mediated inhibition of early events of T cell proliferation.

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23 June 2018

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

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23 June 2018

Diversity of clonal T cell proliferation is mediated by differential expression of CD152 (CTLA-4) on the cell surface of activated individual T lymphocytes.

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31 August 2018

Molecular and functional profiling of memory CD8 T cell differentiation.

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31 August 2018

Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells.

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Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells

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Following the development of a CD4 T cell response in vivo: from activation to memory formation.

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Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

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CTLA-4 regulates induction of anergy in vivo

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1 October 2018

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Polarization of naive CD4+ T cells toward the Th1 subset by CTLA-4 costimulation

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The role of CTLA-4 in regulating Th2 differentiation

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1 October 2018

CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction

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Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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Human Influence on the Atmospheric Vertical Temperature Structure: Detection and Observations

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12 December 2020

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TCR antigen-induced cell death occurs from a late G1 phase cell cycle check point

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https://pubmed.ncbi.nlm.nih.gov/15007096

12 December 2020

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Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15007096

12 December 2020

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Phosphoinositide 3-kinase regulation of T cell receptor-mediated interleukin-2 gene expression in normal T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15007096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1084/JEM.20031058

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25 December 2019

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25 December 2019

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25 December 2019

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