The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action. (Q38780995)

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31 March 2020

title

The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action (English)

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31 March 2020

2

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31 March 2020

Peter Faull

7

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31 March 2020

David Bernard

12

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31 March 2020

author name string

A Griveau

1

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31 March 2020

L Eberst

3

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31 March 2020

N Navaratnam

4

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31 March 2020

B Le Calvé

5

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31 March 2020

M Ferrand

6

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31 March 2020

A Augert

8

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31 March 2020

R Dante

9

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31 March 2020

J M Vanacker

10

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31 March 2020

D Vindrieux

11

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31 March 2020

language of work or name

English

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publication date

4 April 2016

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31 March 2020

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31 March 2020

volume

35

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31 March 2020

issue

38

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31 March 2020

page(s)

5033-5042

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The M-type receptor PLA2R regulates senescence through the p53 pathway

31 March 2020

cites work

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PLA2R1 mediates tumor suppression by activating JAK2.

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PLA2R1 kills cancer cells by inducing mitochondrial stress.

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Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

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Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

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Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand

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ERRs and cancers: effects on metabolism and on proliferation and migration capacities

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Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

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Transcriptional control of the ERBB2 amplicon by ERRalpha and PGC-1beta promotes mammary gland tumorigenesis

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Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin

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Loss of estrogen-related receptor α promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances.

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Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

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ERRα augments HIF-1 signalling by directly interacting with HIF-1α in normoxic and hypoxic prostate cancer cells

21 January 2018

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HIF- and non-HIF-regulated hypoxic responses require the estrogen-related receptor in Drosophila melanogaster

21 January 2018

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The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

21 January 2018

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Repression of osteoblast maturation by ERRα accounts for bone loss induced by estrogen deficiency

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Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells

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HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

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The role of Stat5 transcription factors as tumor suppressors or oncogenes

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27041564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PLA2R1: expression and function in cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27041564