Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition. (Q38968478)

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scientific article published in August 2014

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English	Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition.	scientific article published in August 2014

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scholarly article

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12 March 2020

Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition (English)

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12 March 2020

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cancer cell line

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inferred from title

Marco A de Velasco

6

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12 March 2020

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Akihiro Kogita

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12 March 2020

Yosuke Togashi

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12 March 2020

Hidetoshi Hayashi

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12 March 2020

Shunsuke Sogabe

4

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12 March 2020

Masato Terashima

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12 March 2020

Kazuko Sakai

7

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12 March 2020

Yoshihiko Fujita

8

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12 March 2020

Shuta Tomida

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12 March 2020

Yoshifumi Takeyama

10

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12 March 2020

Kiyotaka Okuno

11

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12 March 2020

Kazuhiko Nakagawa

12

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12 March 2020

Kazuto Nishio

13

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12 March 2020

publication date

1 August 2014

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12 March 2020

International Journal of Oncology

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12 March 2020

45

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12 March 2020

4

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12 March 2020

1430-1436

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12 March 2020

The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer

1 reference

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9 September 2017

Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor

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9 September 2017

Epithelial-mesenchymal transition leads to crizotinib resistance in H2228 lung cancer cells with EML4-ALK translocation

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9 September 2017

Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.

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9 September 2017

CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study

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Regulatory networks defining EMT during cancer initiation and progression

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Cancer statistics, 2013

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Cancer treatment and survivorship statistics, 2012

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Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links

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9 September 2017

Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

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9 September 2017

CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant

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9 September 2017

Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK.

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9 September 2017

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

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EMT: a new vision of hypoxia promoting cancer progression

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9 September 2017

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

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9 September 2017

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

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Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

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SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion

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9 September 2017

Cadherin switching

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9 September 2017

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

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9 September 2017

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

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9 September 2017

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

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9 September 2017

Exploiting tumour hypoxia in cancer treatment

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9 September 2017

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9 September 2017

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Hypoxia--a key regulatory factor in tumour growth

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9 September 2017

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Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

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Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line

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21 August 2018

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10.3892/IJO.2014.2574

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12 March 2020

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12 March 2020

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12 March 2020

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