Molecular and Therapeutic Targets of Genistein in Alzheimer's Disease (Q38994708)

8 September 2017

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title

Molecular and Therapeutic Targets of Genistein in Alzheimer's Disease (English)

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8 September 2017

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Kasi Pandima Devi

1

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8 September 2017

Balakrishnan Shanmuganathan

2

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8 September 2017

Azadeh Manayi

3

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8 September 2017

Seyed Fazel Nabavi

4

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8 September 2017

Seyed Mohammad Nabavi

5

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8 September 2017

publication date

28 October 2016

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8 September 2017

published in

Molecular Neurobiology

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Terpenoids as potential anti-Alzheimer's disease therapeutics.

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Treatment guidelines for Alzheimer's disease: redefining perceptions in primary care

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

A systematic review of assessment and treatment of moderate to severe Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Effects of memantine on cognition in patients with moderate to severe Alzheimer's disease: post-hoc analyses of ADAS-cog and SIB total and single-item scores from six randomized, double-blind, placebo-controlled studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Practice parameter: Management of dementia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Recent developments in Alzheimer's disease therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Chemistry and biochemistry of dietary polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Potential Therapeutic Effects of Oleuropein Aglycone in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Chemical reaction of soybean flavonoids with DNA: a computational study using the implicit solvent model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

A review of the evidence for the use of phytoestrogens as a replacement for traditional estrogen replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soy isoflavone alleviates Aβ1-42-induced impairment of learning and memory ability through the regulation of RAGE/LRP-1 in neuronal and vascular tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soy isoflavone antagonizes the oxidative cerebrovascular injury induced by β-amyloid peptides 1-42 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Production of soybean isoflavone genistein in non-legume plants via genetically modified secondary metabolism pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Measurement of intact sulfate and glucuronide phytoestrogen conjugates in human urine using isotope dilution liquid chromatography-tandem mass spectrometry with [13C(3)]isoflavone internal standards

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein: A Boon for Mitigating Ischemic Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Bioactivity of genistein: A review of in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein decreases cellular redox potential, partially suppresses cell growth in HL‑60 leukemia cells and sensitizes cells to γ‑radiation‑induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Antioxidant and antipromotional effects of the soybean isoflavone genistein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Isoflavones prevent endoplasmic reticulum stress-mediated neuronal degeneration by inhibiting tau hyperphosphorylation in SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein, a dietary-derived inhibitor of in vitro angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Phytoestrogen consumption and risk for cognitive decline and dementia: With consideration of thyroid status and other possible mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Neurobehavioral effects of dietary soy phytoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soybean supplementation helps reverse age- and scopolamine-induced memory deficits in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soybean foods and their benefits: potential mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein and cancer: current status, challenges, and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Molecular effects of genistein on estrogen receptor mediated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein as antioxidant and antibrowning agents in in vivo and in vitro: A review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein, a soy isoflavone, induces glutathione peroxidase in the human prostate cancer cell lines LNCaP and PC-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

The tyrosine kinase inhibitor genistein induces the detachment of rotavirus particles from the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Multi-targeted therapy of cancer by genistein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soya phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Eating soya improves human memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein ameliorates learning and memory deficits in amyloid β(1-40) rat model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

21 January 2018

Dietary phytoestrogens

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https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein ameliorates beta-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Estrogen receptor β in Alzheimer's disease: From mechanisms to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Neuroprotective effects of genistein in Mongolian gerbils: estrogen receptor-β involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Amyloid beta-protein and the genetics of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

100 years and counting: prospects for defeating Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Regulation of integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

The effect of genistein on the content and activity of α- and β-secretase and protein kinase C in Aβ-injured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by beta-amyloid peptides 25-35 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

17beta-Estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Neuroprotective effects of genistein and folic acid on apoptosis of rat cultured cortical neurons induced by beta-amyloid 31-35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein and folic acid prevent oxidative injury induced by β-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPAR gamma expression in cultured astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein alleviates the mitochondria-targeted DNA damage induced by β-amyloid peptides 25-35 in C6 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Chemokines: integrators of pain and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Impact and Therapeutic Potential of PPARs in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Toll-like receptors 2, -3 and -4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1β release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Beta amyloid peptide (25-35) leading to inflammation through Toll-like receptors and the anti-inflammatory effect of genistein in BV-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein alleviates β-amyloid-induced inflammatory damage through regulating Toll-like receptor 4/nuclear factor κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Converging pathogenic mechanisms in vascular and neurodegenerative dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Flavonoids protect cerebrovascular endothelial cells through Nrf2 and PI3K from β-amyloid peptide-induced oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

The Multiple Sclerosis Risk Sharing Scheme Monitoring Study--early results and lessons for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Pre-treatment effect of different doses of soy isoflavones on spatial learning and memory in an ovariectomized animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein inhibits aggregation of exogenous amyloid-beta₁₋₄₀ and alleviates astrogliosis in the hippocampus of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Amyloid beta(1-40)-induced astrogliosis and the effect of genistein treatment in rat: a three-dimensional confocal morphometric and proteomic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Brain endogenous estrogen levels determine responses to estrogen replacement therapy via regulation of BACE1 and NEP in female Alzheimer's transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Clearing Amyloid-β through PPARγ/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Genistein improves spatial learning and memory in male rats with elevated glucose level during memory consolidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Hormone replacement therapy (HRT)--risks and benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Effects of genistein and daidzein on hippocampus neuronal cell proliferation and BDNF expression in H19-7 neural cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Targeting estrogen receptors for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Acute, subchronic and chronic safety studies with genistein in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0215-6

Inhibition of tyrosine protein kinase activity by synthetic isoflavones and flavones

21 January 2018

1 reference

12 December 2020

Genistein, a specific inhibitor of tyrosine-specific protein kinases

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12 December 2020

Daidzein and genistein but not their glucosides are absorbed from the rat stomach

1 reference

12 December 2020

Effect of estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth factor mRNAs in the frontal cortex and hippocampus of female rats

1 reference

12 December 2020

Neither background diet nor type of soy food affects short-term isoflavone bioavailability in women

1 reference

12 December 2020

Inhibition of UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A431 cells by genistein

1 reference

12 December 2020

Soy phytoestrogens improve radial arm maze performance in ovariectomized retired breeder rats and do not attenuate benefits of 17beta-estradiol treatment.

1 reference

12 December 2020

Daidzein and genistein content of fruits and nuts

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12 December 2020

Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements

1 reference

12 December 2020

Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability

1 reference

12 December 2020

Isoflavonoid and lignan phytoestrogens as dietary biomarkers.

1 reference

12 December 2020

Bioavailability of phyto-oestrogens

1 reference

12 December 2020

Bioavailability of soybean isoflavones from aglycone and glucoside forms in American women

1 reference

12 December 2020

Polyphenols: food sources and bioavailability

1 reference

12 December 2020

Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies

1 reference

12 December 2020

Bioavailability of genistein and its glycoside genistin as measured in the portal vein of freely moving unanesthetized rats

1 reference

12 December 2020

Effect of dietary genistein on Phase II and antioxidant enzymes in rat liver

1 reference

12 December 2020

The basics of preclinical drug development for neurodegenerative disease indications

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12 December 2020

Plasma pharmacokinetics of genistein in mice

1 reference

12 December 2020

Genistein inhibits mitochondrial-targeted oxidative damage induced by beta-amyloid peptide 25-35 in PC12 cells

1 reference

12 December 2020

Genistein downregulates presenilin 1 and ubiquilin 1 expression

1 reference

12 December 2020

Apoptosis and oxidative stress in neurodegenerative diseases.

1 reference

12 December 2020

10.1007/S12035-016-0215-6

Identifiers

DOI

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Dimensions Publication ID

1040847914

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