Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice (Q39127345)

9 September 2017

title

Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice (English)

1 reference

9 September 2017

Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5042

30 March 2024

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5042

30 March 2024

author name string

Ninan Abraham

2

1 reference

9 September 2017

Jonathan W. Snow

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607901

30 March 2024

Melissa C. Ma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607901

30 March 2024

Brian G. Herndier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607901

30 March 2024

Alexander W. Pastuszak

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607901

30 March 2024

Mark A. Goldsmith

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607901

30 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

9 September 2017

15 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14607901

full work available at URL

30 March 2024

published in

Journal of Immunology

1 reference

9 September 2017

volume

171

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9 September 2017

issue

10

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9 September 2017

page(s)

5042-5050

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Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

9 September 2017

cites work

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1016/S1074-7613(00)80103-X

Autoimmune disease: why and where it occurs.

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Cytokines and autoimmunity

30 March 2024

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Thymus and tolerance. Is regulation the major function of the thymus?

30 March 2024

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CD4+ T-cell subsets in autoimmunity

30 March 2024

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Cytokines that regulate autoimmune responses.

30 March 2024

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Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

30 March 2024

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Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

30 March 2024

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Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

30 March 2024

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Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

30 March 2024

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The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis

30 March 2024

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Signaling domains of the interleukin 2 receptor

30 March 2024

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The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

30 March 2024

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Interleukin-2 signaling and the maintenance of self-tolerance

30 March 2024

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The role of STATs in transcriptional control and their impact on cellular function

30 March 2024

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STATs: signal transducers and activators of transcription

30 March 2024

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Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

30 March 2024

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Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

30 March 2024

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

30 March 2024

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Stat5a is mandatory for adult mammary gland development and lactogenesis.

30 March 2024

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

30 March 2024

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An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

30 March 2024

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Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

30 March 2024

23

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STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells

30 March 2024

24

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Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5.

30 March 2024

25

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Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

30 March 2024

26

1 reference

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

30 March 2024

27

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

30 March 2024

28

1 reference

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Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells

30 March 2024

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

30 March 2024

31

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Stat5a regulates T helper cell differentiation by several distinct mechanisms

30 March 2024

33

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Preparation and characterization of an endogenously fluorescent annexin for detection of apoptotic cells.

30 March 2024

36

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

30 March 2024

37

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

30 March 2024

38

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Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

30 March 2024

41

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Interleukin 2 signaling is required for CD4(+) regulatory T cell function

30 March 2024

42

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CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

30 March 2024

43

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Regulatory T cells in the control of immune pathology.

30 March 2024

44

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CD4+ CD25+ suppressor T cells: more questions than answers

30 March 2024

45

1 reference

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

30 March 2024

46

1 reference

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CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

30 March 2024

47

1 reference

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The pathophysiology of acquired aplastic anemia

30 March 2024

48

1 reference

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Autoimmune disorders of erythropoiesis

30 March 2024

50

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Effector lymphocytes in autoimmunity

30 March 2024

52

1 reference

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Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models

30 March 2024

53

1 reference

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Dissecting the role of CD4+ T cells in autoimmune diabetes through the use of TCR transgenic mice

30 March 2024

54

1 reference

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Functional dissection of the cytoplasmic subregions of the IL-2 receptor betac chain in primary lymphocyte populations

30 March 2024

55

1 reference

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The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

30 March 2024

56

1 reference

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Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo

30 March 2024

58

1 reference

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Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms

30 March 2024

59

1 reference

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

30 March 2024

60

1 reference

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

30 March 2024

61

1 reference

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Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

30 March 2024

63

1 reference

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The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

30 March 2024

65

1 reference

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The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements

30 March 2024

66

1 reference

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30 March 2024

Identifiers

1 reference

9 September 2017

1 reference