Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents (Q39453785)

12 September 2017

title

Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents (English)

1 reference

12 September 2017

0 references

0 references

Alawi H Habara

1

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Elmutaz M Shaikho

object named as

Elmutaz M Shaikho

series ordinal

2

0 references

Martin H Steinberg

object named as

Martin H Steinberg

series ordinal

3

0 references

publication date

24 July 2017

1 reference

American Journal of Hematology

12 September 2017

published in

1 reference

Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemia

12 September 2017

cites work

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15 September 2018

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Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus

15 September 2018

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15 September 2018

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15 September 2018

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15 September 2018

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15 September 2018

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15 September 2018

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An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

15 September 2018

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15 September 2018

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Fetal Haemoglobin and β-globin Gene Cluster Haplotypes among Sickle Cell Patients in Chhattisgarh

15 September 2018

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Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype

15 September 2018

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Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

15 September 2018

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Clinical management of adult sickle-cell disease.

15 September 2018

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15 September 2018

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15 September 2018

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MicroRNA-96 directly inhibits γ-globin expression in human erythropoiesis

15 September 2018

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Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans

15 September 2018

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Fetal hemoglobin in sickle cell anemia

15 September 2018

1 reference

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A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

15 September 2018

1 reference

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Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Transcriptional silencing of fetal hemoglobin by BCL11A.

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex

15 September 2018

1 reference

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How I use hydroxyurea to treat young patients with sickle cell anemia

15 September 2018

1 reference

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Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

15 September 2018

1 reference

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The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS).

15 September 2018

1 reference

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Control of fetal hemoglobin: new insights emerging from genomics and clinical implications

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

The prevalence of sickle cell disease in Saudi children and adolescents. A community-based survey.

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

15 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Consanguinity and major genetic disorders in Saudi children: a community-based cross-sectional study.

15 September 2018

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Clinical effectiveness of decitabine in severe sickle cell disease

15 September 2018

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Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia

15 September 2018

1 reference

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Understanding mechanisms of gamma-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction

15 September 2018

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DNA hypomethylation therapy for hemoglobin disorders: molecular mechanisms and clinical applications

15 September 2018

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The Corfu deltabeta thalassemia deletion disrupts gamma-globin gene silencing and reveals post-transcriptional regulation of HbF expression

15 September 2018

1 reference

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Mortality in sickle cell patients on hydroxyurea therapy

15 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment

15 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5647233

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

15 September 2018

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Senegal haplotype is associated with higher HbF than Benin and Cameroon haplotypes in African children with sickle cell anemia

15 September 2018

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Consanguinity among the Saudi Arabian population

15 September 2018

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Sickle beta 0 thalassemia in Eastern Saudi Arabia

15 September 2018

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Hematologically and genetically distinct forms of sickle cell anemia in Africa. The Senegal type and the Benin type

15 September 2018

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Natural history of sickle cell anemia in Saudi Arabs. A study of 270 subjects

15 September 2018

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15 September 2018

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Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia

21 January 2018

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Fetal hemoglobin in sickle cell anemia: a glass half full?

21 January 2018

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https://api.crossref.org/works/10.1002%2FAJH.24872

Variation in fetal hemoglobin parameters and predicted hemoglobin S polymerization in sickle cell children in the first two years of life: Parisian Prospective Study on Sickle Cell Disease

21 January 2018

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12 December 2020

Benign sickle-cell anaemia

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12 December 2020

Neonatal screening for sickle cell disease, glucose-6-phosphate dehydrogenase deficiency and a-thalassemia in Qatif and Al Hasa

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12 December 2020

RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model

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12 December 2020

An analysis of fetal hemoglobin variation in sickle cell disease: the relative contributions of the X-linked factor, beta-globin haplotypes, alpha-globin gene number, gender, and age

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12 December 2020

Identifiers

DOI

10.1002/AJH.24872

1 reference

12 September 2017

0 references

1 reference