miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy (Q39465507)

12 September 2017

title

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy (English)

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Gianfranco Mattia

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Piero Picci

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Piero Picci

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Massimo Negrini

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Massimo Negrini

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Maria Cristina Manara

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Maria Cristina Manara

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Marco Alberghini

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Katia Scotlandi

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Selena Ventura

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Sakari Knuutila

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Fumihiko Nakatani

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Valentina Del Monaco

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Stefano Ferrari

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Andrea Grilli

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Karl-Ludwig Schaefer

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publication date

1 April 2012

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volume

226

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issue

5

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page(s)

796-805

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Mechanisms of sarcoma development

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cites work

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EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

21 January 2018

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Identification of cancer stem cells in Ewing's sarcoma

21 January 2018

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Mesenchymal stem cell features of Ewing tumors

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Approaching Ewing sarcoma

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Bone and soft tissue sarcomas are often curable--but at what cost?: a call to arms (and legs).

21 January 2018

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MicroRNAs: genomics, biogenesis, mechanism, and function

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miRNAs as molecular biomarkers of cancer

21 January 2018

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Micromarkers: miRNAs in cancer diagnosis and prognosis.

21 January 2018

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Unique MicroRNA signature and clinical outcome of cancers

21 January 2018

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Prognostic factors in non-metastatic Ewing's sarcoma tumor of bone: an analysis of 579 patients treated at a single institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1998.

21 January 2018

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Power and sample size calculations for studies involving linear regression

21 January 2018

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Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid tissues

21 January 2018

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Semi-supervised methods to predict patient survival from gene expression data

21 January 2018

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A microRNA component of the p53 tumour suppressor network

21 January 2018

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Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

21 January 2018

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The miR-34 family in cancer and apoptosis

21 January 2018

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Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse

21 January 2018

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Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy

21 January 2018

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21 January 2018

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Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 January 2018

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Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

21 January 2018

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Intercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcoma

21 January 2018

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Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

21 January 2018

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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

21 January 2018

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MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

21 January 2018

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Functional elucidation of MiR-34 in osteosarcoma cells and primary tumor samples

21 January 2018

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Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest

21 January 2018

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MicroRNAs: predictors and modifiers of chemo- and radiotherapy in different tumour types

21 January 2018

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The guardian's little helper: microRNAs in the p53 tumor suppressor network

21 January 2018

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p53 enters the microRNA world

21 January 2018

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Inhibition of the transcriptional function of p53 by EWS-Fli1 chimeric protein in Ewing Family Tumors

21 January 2018

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Nutlin-3a is a potential therapeutic for ewing sarcoma

21 January 2018

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MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

21 January 2018

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Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

21 January 2018

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The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

21 January 2018

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Nonmetastatic Ewing family tumors: high-dose chemotherapy with stem cell rescue in poor responder patients. Results of the Italian Sarcoma Group/Scandinavian Sarcoma Group III protocol

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.3007

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12 September 2017

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