Maximizing productivity of CHO cell‐based fed‐batch culture using chemically defined media conditions and typical manufacturing equipment (Q39644298)

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scientific article published on September 1, 2010

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English	Maximizing productivity of CHO cell‐based fed‐batch culture using chemically defined media conditions and typical manufacturing equipment	scientific article published on September 1, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Maximizing productivity of CHO cell‐based fed‐batch culture using chemically defined media conditions and typical manufacturing equipment (English)

1 reference

10.1002/BTPR.436

https://api.crossref.org/works/10.1002/BTPR.436

2 August 2024

author name string

Yao-Ming Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

WeiWei Hu

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Eddie Rustandi

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Kevin Chang

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Helena Yusuf-Makagiansar

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Thomas Ryll

6

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20945494

2 August 2024

publication date

1 September 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

full work available at URL

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbtpr.436

1 reference

10.1002/BTPR.436

https://api.crossref.org/works/10.1002/BTPR.436

2 August 2024

https://onlinelibrary.wiley.com/doi/full/10.1002/btpr.436

1 reference

10.1002/BTPR.436

https://api.crossref.org/works/10.1002/BTPR.436

2 August 2024

Biotechnology Progress

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1400-1410

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Effects of methotrexate on transfected DNA stability in mammalian cells

1 reference

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Process economics of industrial monoclonal antibody manufacture

1

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Therapeutic antibody expression technology

2

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Therapeutic potential of neutralizing antibodies in the treatment of HIV-1 infection

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Recombinant antibodies for cancer diagnosis and therapy

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B cells as therapeutic targets in autoimmune neurological disorders

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Industrial choices for protein production by large-scale cell culture

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Stability of protein production from recombinant mammalian cells

8

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Production of recombinant protein therapeutics in cultivated mammalian cells

9

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Antibody production

10

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Conversion of a CHO cell culture process from perfusion to fed-batch technology without altering product quality.

11

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The "push-to-low" approach for optimization of high-density perfusion cultures of animal cells

12

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Controlled shear affinity filtration (CSAF): a new technology for integration of cell separation and protein isolation from mammalian cell cultures

13

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Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention: characterization of separation efficiency and impact of perfusion on product quality

14

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Peptone, a low-cost growth-promoting nutrient for intensive animal cell culture

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Identification of novel small molecule enhancers of protein production by cultured mammalian cells

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A novel function for selenium in biological system: selenite as a highly effective iron carrier for Chinese hamster ovary cell growth and monoclonal antibody production.

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Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues

18

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Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells

19

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Bcl-x(L) mediates increased production of humanized monoclonal antibodies in Chinese hamster ovary cells

21

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Apoptosis in cell culture

22

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Continuous hybridoma growth and monoclonal antibody production in hollow fiber reactors-separators

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Culture of human tumor infiltrating lymphocytes in hollow fiber bioreactors

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Improving performance of mammalian cells in fed-batch processes through "bioreactor evolution".

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Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells.

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Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes

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Fabrication and use of a transient contractional flow device to quantify the sensitivity of mammalian and insect cells to hydrodynamic forces

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Measurement of volumetric (OUR) and determination of specific (qO2) oxygen uptake rates in animal cell cultures

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An investigation of small-molecule surfactants to potentially replace pluronic F-68 for reducing bubble-associated cell damage

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Stoichiometric analysis of animal cell growth and its application in medium design.

35

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Biochemistry of growth inhibition by ammonium ions in mammalian cells

36

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Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese hamster ovary cells

37

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Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms

38

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Effect of ammonia on the glycosylation of human recombinant erythropoietin in culture

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Oxygen limitation is a pitfall during screening for industrial strains.

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Controlling deamidation rates in a model peptide: effects of temperature, peptide concentration, and additives

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Deamidation of human proteins

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Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture

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Reactor engineering in large scale animal cell culture

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Effects of elevated pCO2 and osmolality on growth of CHO cells and production of antibody-fusion protein B1: a case study

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Dependence on glucose limitation of the pCO2 influences on CHO cell growth, metabolism and IgG production.

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Strategies for improved dCO2 removal in large-scale fed-batch cultures

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Decreased pCO(2) accumulation by eliminating bicarbonate addition to high cell-density cultures.

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Effects of cell density and temperature on oxygen consumption rate for different mammalian cell lines

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Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxygen demand in hybridoma cultures

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A comparison of different methods to determine the end of exponential growth in CHO cell cultures for optimization of scale-up.

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Fed-batch culture of recombinant NS0 myeloma cells with high monoclonal antibody production

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Scale-up analysis for a CHO cell culture process in large-scale bioreactors.

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Identifiers

10.1002/BTPR.436

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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