Production of Functional Glucagon-Secreting α-Cells From Human Embryonic Stem Cells (Q39640477)

13 September 2017

Production of functional glucagon-secreting α-cells from human embryonic stem cells (English)

1 reference

https://api.crossref.org/works/10.2337/DB10-0573

13 September 2017

Production of Functional Glucagon-Secreting α-Cells From Human Embryonic Stem Cells (English)

1 reference

human embryonic stem cell

9 August 2024

main subject

1 reference

7

Timothy J Kieffer

1 reference

13 September 2017

Alireza Rezania

1

1 reference

13 September 2017

Francis Karanu

4

1 reference

13 September 2017

Ziliang Ao

5

1 reference

13 September 2017

Michael J. Riedel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

9 August 2024

Rhonda D. Wideman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

9 August 2024

Garth L. Warnock

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

9 August 2024

language of work or name

English

0 references

publication date

22 October 2010

1 reference

13 September 2017

9

1 reference

full work available at URL

inferred from page(s)

http://diabetes.diabetesjournals.org/content/diabetes/60/1/239.full.pdf

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

http://intl-diabetes.diabetesjournals.org/cgi/content/abstract/60/1/239

9 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20971966/?tool=EBI

9 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20971966/pdf/?tool=EBI

9 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

https://europepmc.org/articles/PMC3012176

9 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

https://europepmc.org/articles/PMC3012176?pdf=render

9 August 2024

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20971966

https://journals.org/diabetes/diabetes/article-pdf/60/1/239/400278/zdb00111000239.pdf

9 August 2024

https://api.crossref.org/works/10.2337/DB10-0573

1 reference

https://diabetesjournals.org/diabetes/article-pdf/60/1/239/400278/zdb00111000239.pdf

9 August 2024

https://api.crossref.org/works/10.2337/DB10-0573

1 reference

9 August 2024

1 reference

13 September 2017

60

1 reference

13 September 2017

1

1 reference

13 September 2017

239-247

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

13 September 2017

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

14 September 2017

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14 September 2017

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14 September 2017

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Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

14 September 2017

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14 September 2017

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The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

14 September 2017

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The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

14 September 2017

1 reference

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FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development

14 September 2017

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Opposing actions of Arx and Pax4 in endocrine pancreas development

14 September 2017

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Depletion of definitive gut endoderm in Sox17-null mutant mice

14 September 2017

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Feeder-free growth of undifferentiated human embryonic stem cells

14 September 2017

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Regulation of pancreas development by hedgehog signaling

14 September 2017

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Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

14 September 2017

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

14 September 2017

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Anterior definitive endoderm from ESCs reveals a role for FGF signaling

14 September 2017

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14 September 2017

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Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

14 September 2017

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Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.

14 September 2017

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15 June 2018

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15 June 2018

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15 June 2018

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The midgestational human fetal pancreas contains cells coexpressing islet hormones

15 June 2018

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Geron gets green light for human trial of ES cell-derived product

15 June 2018

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21 August 2018

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A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.

21 August 2018

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Generation of insulin-producing islet-like clusters from human embryonic stem cells.

21 August 2018

1 reference

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Directed differentiation of human embryonic stem cells towards a pancreatic cell fate.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

In vitro derivation of functional insulin-producing cells from human embryonic stem cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012176

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

21 August 2018

1 reference

12 December 2020

Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus

1 reference

12 December 2020

Transient coappearance of glucagon and insulin in the progenitor cells of the rat pancreatic islets

1 reference

12 December 2020

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

12 December 2020

Mutant neurogenin-3 in congenital malabsorptive diarrhea

1 reference

12 December 2020

Expression of Id1 in adult, regenerating and developing pancreas

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-0573

1 reference

13 September 2017

0 references

1 reference

13 September 2017

1 reference