Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence (Q39674577)

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scientific article published on May 2002

Language	Label	Description	Also known as
English	Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence	scientific article published on May 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

author name string

Weiping Wang

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Joan X Chen

2

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Europe PubMed Central

PMC publication ID

13 September 2017

Rong Liao

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Qingdong Deng

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jennifer J Zhou

5

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Europe PubMed Central

PMC publication ID

13 September 2017

Shuang Huang

6

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Europe PubMed Central

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13 September 2017

Peiqing Sun

7

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Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

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publication date

1 May 2002

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Europe PubMed Central

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13 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

13 September 2017

22

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Europe PubMed Central

PMC publication ID

13 September 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

3389-3403

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Mammalian MAP kinase signalling cascades

1 reference

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Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

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Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

1 reference

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p38 MAP kinases: beyond the stress response

1 reference

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Regulation of carbamoyl phosphate synthetase by MAP kinase

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Creation of human tumour cells with defined genetic elements

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Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3.

1 reference

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Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

1 reference

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

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Senescence of human fibroblasts induced by oncogenic Raf.

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

1 reference

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Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

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Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

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Identification and characterization of a predominant isoform of human MKK3.

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

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Complex formation between RAS and RAF and other protein kinases

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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RAS Signalling Is Abnormal in a c-raf1 MEK1 Double Mutant

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/11971971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b

1 reference

https://pubmed.ncbi.nlm.nih.gov/11971971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.22.10.3389-3403.2002

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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