Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin. (Q39735993)

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18 January 2020

title

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin (English)

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18 January 2020

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2

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18 January 2020

Naoya Yahagi

12

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18 January 2020

author name string

Takashi Yamamoto

1

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18 January 2020

Noriyuki Inoue

3

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18 January 2020

Yoshimi Nakagawa

4

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18 January 2020

Naomi Ishigaki

5

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18 January 2020

Takashi Matsuzaka

6

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18 January 2020

Yoshinori Takeuchi

7

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18 January 2020

Kazuto Kobayashi

8

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18 January 2020

Shigeru Yatoh

9

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18 January 2020

Akimitsu Takahashi

10

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18 January 2020

Hiroaki Suzuki

11

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18 January 2020

Takanari Gotoda

13

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18 January 2020

Nobuhiro Yamada

14

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18 January 2020

Hitoshi Shimano

15

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18 January 2020

publication date

23 February 2010

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Journal of Lipid Research

18 January 2020

published in

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18 January 2020

volume

51

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18 January 2020

issue

7

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18 January 2020

page(s)

1859-1870

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The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity

18 January 2020

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Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

14 September 2017

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Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

14 September 2017

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O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability

14 September 2017

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SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

14 September 2017

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Sterol regulatory element-binding protein-1 as a dominant transcription factor for gene regulation of lipogenic enzymes in the liver

14 September 2017

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Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

14 September 2017

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Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

14 September 2017

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14 September 2017

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14 September 2017

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Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

14 September 2017

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Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

14 September 2017

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Functional role for protein kinase Cbeta as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Regulation of the low density lipoprotein receptor and hydroxymethylglutaryl coenzyme A reductase genes by protein kinase C and a putative negative regulatory protein

14 September 2017

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Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).

14 September 2017

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14 September 2017

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Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway

14 September 2017

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Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene

14 September 2017

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Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements

25 September 2017

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Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

17 June 2018

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Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.

17 June 2018

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SREBPs suppress IRS-2-mediated insulin signalling in the liver

20 August 2018

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Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

20 August 2018

1 reference

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Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

20 August 2018

1 reference

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Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

20 August 2018

1 reference

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Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M004234

Lipotoxicity: the obese and endurance-trained paradox

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20179320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein kinase C deficiency increases fatty acid oxidation and reduces fat storage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20179320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M004234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179320%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179320%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20179320

1 reference