Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells. (Q39811938)

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English	Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells.	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19685010%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19685010%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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Katarzyna Grzelkowska-Kowalczyk

1

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5 February 2020

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Wioletta Wieteska-Skrzeczyńska

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5 February 2020

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14 August 2009

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5 February 2020

Cellular & Molecular Biology Letters

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5 February 2020

15

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5 February 2020

1

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5 February 2020

13-31

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19685010%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

TNFalpha mediates sepsis-induced impairment of basal and leucine-stimulated signaling via S6K1 and eIF4E in cardiac muscle

1 reference

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Skeletal Muscle wasting and contractile performance in septic rats.

1 reference

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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

1 reference

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Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

1 reference

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Tumor necrosis factor-{alpha} decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt.

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Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4.

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The effect of tumor necrosis factor-alpha on tissue specificity and selectivity to insulin signaling

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Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells

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IGF-1, inflammation and stem cells: interactions during muscle regeneration.

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Differential signalling mechanisms predisposing primary human skeletal muscle cells to altered proliferation and differentiation: roles of IGF-I and TNFalpha

1 reference

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The role of cytokines in regulating protein metabolism and muscle function

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Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies

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Circulating adiponectin levels during human endotoxaemia

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Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

1 reference

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IFN-gamma prevents TNF-alpha-induced apoptosis in C2C12 myotubes through down-regulation of TNF-R2 and increased NF-kappaB activity

1 reference

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TNF-alpha inhibits adult fast myosin accumulation in myotubes

1 reference

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Regulation of skeletal-muscle-protein turnover in cancer-associated cachexia

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IFN-gamma does not mimic the catabolic effects of TNF-alpha

1 reference

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21 January 2018

Acute moderate elevation of TNF-alpha does not affect systemic and skeletal muscle protein turnover in healthy humans

1 reference

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Cytokines and chemokines are both expressed by human myoblasts: possible relevance for the immune pathogenesis of muscle inflammation

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Activation of Ca(2+)-dependent proteolysis in skeletal muscle and heart in cancer cachexia

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TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0033-1

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A central role for JNK in obesity and insulin resistance

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Acute treatment with TNF-alpha attenuates insulin-stimulated protein synthesis in cultures of C2C12 myotubes through a MEK1-sensitive mechanism.

1 reference

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21 January 2018

Tumor Necrosis Factor-α Decreases Insulin-Like Growth Factor-I Messenger Ribonucleic Acid Expression in C2C12 Myoblasts via a Jun N-Terminal Kinase Pathway

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Signalling through IGF-I and insulin receptors: where is the specificity?

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21 January 2018

Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts

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Elevation of cytokine levels in cachectic patients with prostate carcinoma

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Exposure to TNF-alpha but not IL-1beta impairs insulin-dependent phosphorylation of protein kinase B and p70S6k in mouse C2C12 myogenic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19685010

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Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes

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Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscle

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The impairment of IGF-I-stimulated protein synthesis and activation of protein kinase B, p70(S6k), MAP kinase, and p90(rsk) in mouse C2C12 myogenic cells exposed to high glucose and high insulin

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10.2478/S11658-009-0033-1

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Europe PubMed Central

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5 February 2020

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9 September 2019

https://scigraph.springernature.com/pub.10.2478/s11658-009-0033-1

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Europe PubMed Central

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5 February 2020

PubMed publication ID

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Europe PubMed Central

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5 February 2020

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