Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice. (Q30437121)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20140187%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice (English)

1 reference

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17 January 2020

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3

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17 January 2020

author name string

Shuqiu Zheng

1

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17 January 2020

Erin B D Clabough

2

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17 January 2020

Marie Futter

4

1 reference

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17 January 2020

David C Rubinsztein

5

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17 January 2020

Scott O Zeitlin

6

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17 January 2020

publication date

5 February 2010

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17 January 2020

1 reference

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17 January 2020

volume

6

1 reference

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17 January 2020

issue

2

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17 January 2020

page(s)

e1000838

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Creative Commons Attribution 4.0 International

17 January 2020

copyright license

start time

5 February 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2816686/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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28 July 2018

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28 July 2018

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Deletion of the triplet repeat encoding polyglutamine within the mouse Huntington's disease gene results in subtle behavioral/motor phenotypes in vivo and elevated levels of ATP with cellular senescence in vitro

28 July 2018

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Normal huntingtin function: an alternative approach to Huntington's disease

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

28 July 2018

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28 July 2018

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Comparative sequence analysis of the human and pufferfish Huntington's disease genes

28 July 2018

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Studies on brain biopsies of patients with Huntington's chorea

28 July 2018

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Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease

28 July 2018

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Clinical and neuropathologic assessment of severity in Huntington's disease

28 July 2018

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Neuropathological classification of Huntington's disease

28 July 2018

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Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat

28 July 2018

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Juvenile Huntington chorea: Clinical, ultrastructural, and biochemical studies

28 July 2018

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Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains

28 July 2018

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HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans.

21 January 2018

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In search of an "autophagomometer".

21 January 2018

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A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes

21 January 2018

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Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

A molecular investigation of true dominance in Huntington's disease

21 January 2018

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

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The lysosomal-mitochondrial axis theory of postmitotic aging and cell death

21 January 2018

1 reference

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Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000838

Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816686

10.1371/JOURNAL.PGEN.1000838

26 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20140187%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20140187%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

20140187

1 reference