CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse (Q30478206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16339518%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse (English)

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10 January 2020

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3

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10 January 2020

Mengling Liu

series ordinal

2

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10 January 2020

author name string

Su-Yi Tseng

series ordinal

1

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10 January 2020

language of work or name

English

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publication date

1 December 2005

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10 January 2020

published in

Journal of Immunology

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10 January 2020

volume

175

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10 January 2020

issue

12

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10 January 2020

page(s)

7829-7836

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Crystal structure of a soluble CD28-Fab complex

10 January 2020

cites work

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

20 June 2018

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Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte-associated antigen 4.

20 June 2018

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CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

20 June 2018

1 reference

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T cell receptor signaling precedes immunological synapse formation

20 June 2018

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Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

20 June 2018

1 reference

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The immunological synapse and CD28-CD80 interactions.

20 June 2018

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation

20 June 2018

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A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

20 June 2018

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NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

20 June 2018

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B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha

20 June 2018

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A T cell receptor-specific blockade of positive selection

20 June 2018

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Molecular basis of T cell inactivation by CTLA-4

20 June 2018

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

20 June 2018

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Three-dimensional segregation of supramolecular activation clusters in T cells

20 June 2018

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Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

20 June 2018

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Dendritic cells and the control of immunity

20 June 2018

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The emerging role of CTLA-4 as an immune attenuator

20 June 2018

1 reference

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CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1626532

Subcellular localization of CD80 receptors is dependent on an intact cytoplasmic tail and is required for CD28-dependent T cell costimulation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1626532

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

20 June 2018

1 reference

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T cell activation determined by T cell receptor number and tunable thresholds.

20 June 2018

1 reference

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CTLA-4 can function as a negative regulator of T cell activation

20 June 2018

1 reference

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

20 June 2018

1 reference

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

20 June 2018

1 reference

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

20 June 2018

1 reference

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Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

20 June 2018

1 reference

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Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH

20 June 2018

1 reference

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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

20 June 2018

1 reference

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

20 June 2018

1 reference

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B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

20 June 2018

1 reference

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CD28 signals in the immature immunological synapse

26 November 2018

1 reference

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The immunological synapse balances T cell receptor signaling and degradation

26 November 2018

1 reference

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Regulation of Lck activity by CD4 and CD28 in the immunological synapse

26 November 2018

1 reference

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Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

26 November 2018

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Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

26 November 2018

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Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population

26 November 2018

1 reference

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Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

26 November 2018

1 reference

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Activation of CD4+ T cells by delivery of the B7 costimulatory signal on bystander antigen-presenting cells (trans-costimulation).

26 November 2018

1 reference

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Live-cell dynamics and the role of costimulation in immunological synapse formation

26 November 2018

1 reference

12 December 2020

Cutting Edge: Dendritic Cell Actin Cytoskeletal Polarization during Immunological Synapse Formation Is Highly Antigen-Dependent

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12 December 2020

Requirement of Rac1 and Rac2 Expression by Mature Dendritic Cells for T Cell Priming

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12 December 2020

Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation

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12 December 2020

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

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12 December 2020

CD28 is an inducible T cell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes

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12 December 2020

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

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12 December 2020

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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12 December 2020

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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12 December 2020

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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12 December 2020

Characterization of endogenous Chinese hamster ovary cell surface molecules that mediate T cell costimulation

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12 December 2020

CD28 Signaling via VAV/SLP-76 Adaptors

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12 December 2020

The dendritic cell cytoskeleton is critical for the formation of the immunological synapse

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12 December 2020

Rejection of mouse cardiac allografts by costimulation in trans

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12 December 2020

10.4049/JIMMUNOL.175.12.7829

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16339518%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16339518%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

16339518

1 reference