Human models as tools in the development of psychotropic drugs (Q30473426)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034241%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Human models as tools in the development of psychotropic drugs (English)

1 reference

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15 January 2020

author name string

Christian Gilles

1

1 reference

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15 January 2020

Thérèse Schunck

2

1 reference

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15 January 2020

Gilles Erb

3

1 reference

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15 January 2020

Izzie Jacques Namer

4

1 reference

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15 January 2020

Yann Hodé

5

1 reference

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15 January 2020

Jean-François Nedelec

6

1 reference

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15 January 2020

Peter Boeijinga

7

1 reference

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15 January 2020

Remy Luthringer

8

1 reference

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15 January 2020

Jean-Paul Mâcher

9

1 reference

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15 January 2020

publication date

1 December 2002

1 reference

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Dialogues in Clinical Neuroscience

15 January 2020

published in

1 reference

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15 January 2020

volume

4

1 reference

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15 January 2020

issue

4

1 reference

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15 January 2020

page(s)

377-387

1 reference

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Sleep-wake mechanisms and drug discovery: sleep EEG as a tool for the development of CNS-acting drugs.

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Pharmacological models in Alzheimer's disease research

14 July 2018

1 reference

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Studies in schizophrenia: pathophysiology and treatment

14 July 2018

1 reference

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Functional MRI detection of pharmacologically induced memory impairment

14 July 2018

1 reference

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Vigabatrin decreases cholecystokinin-tetrapeptide (CCK-4) induced panic in healthy volunteers

14 July 2018

1 reference

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Effects of ketamine in normal and schizophrenic volunteers

14 July 2018

1 reference

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Symptom provocation studies in psychiatric disorders: scientific value, risks, and future

14 July 2018

1 reference

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Electroencephalographic and psychomotor effects of chlorpromazine and risperidone relative to placebo in normal healthy volunteers

14 July 2018

1 reference

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Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala

14 July 2018

1 reference

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CCK4-induced panic in healthy subjects I: psychological and cardiovascular effects

14 July 2018

1 reference

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Electroencephalographic characterization of brain dopaminergic stimulation by apomorphine in healthy volunteers

14 July 2018

1 reference

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Central effects of acamprosate: part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers

14 July 2018

1 reference

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Brain systems mediating aversive conditioning: an event-related fMRI study

14 July 2018

1 reference

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Human amygdala activation during conditioned fear acquisition and extinction: a mixed-trial fMRI study

14 July 2018

1 reference

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Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers

14 July 2018

1 reference

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The effect of cholecystokinin tetrapeptide on respiratory resistance in healthy volunteers

14 July 2018

1 reference

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Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory

14 July 2018

1 reference

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Pharmacoelectroencephalographic profile of befloxatone, a new reversible MAO-A inhibitor, in healthy subjects

14 July 2018

1 reference

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Multilead quantitative EEG profile of clozapine in resting and vigilance-controlled conditions

14 July 2018

1 reference

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Cognitive effects of scopolamine in dementia.

14 July 2018

1 reference

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The effects of a benzodiazepine receptor antagonist beta-carboline ZK-93426 on scopolamine-induced impairment on attention, memory and psychomotor skills

14 July 2018

1 reference

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Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers

14 July 2018

1 reference

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Subanesthetic doses of ketamine stimulate psychosis in schizophrenia

14 July 2018

1 reference

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Effects of acute doses of oxiracetam in the scopolamine model of human amnesia

14 July 2018

1 reference

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Effects of hypnotics on memory.

14 July 2018

1 reference

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Benzodiazepines antagonize cholecystokinin-induced activation of rat hippocampal neurones

14 July 2018

1 reference

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Mental dysfunction and the blockade of muscarinic receptors in the brains of the normal elderly

14 July 2018

1 reference

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Interaction of choline and scopolamine in human memory.

14 July 2018

1 reference

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Ketamine: behavioral effects of subanesthetic doses

14 July 2018

1 reference

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Scopolamine challenges in Alzheimer's disease

14 July 2018

1 reference

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Anticholinergic sensitivity in patients with dementia of the Alzheimer type and age-matched controls. A dose-response study

14 July 2018

1 reference

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Effects of lorazepam on memory, attention and sedation in man.

14 July 2018

1 reference

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Differential amnesic properties of benzodiazepines: a dose-response comparison of two drugs with similar elimination half-lives

14 July 2018

1 reference

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Models of memory dysfunctions

14 July 2018

1 reference

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The amnesic action of benzodiazepines in man.

14 July 2018

1 reference

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Cholecystokinin tetrapeptide induces panic-like attacks in healthy volunteers. Preliminary findings

14 July 2018

1 reference

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The effects of moclobemide on cognition

14 July 2018

1 reference

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Scopolamine and benzodiazepine models of dementia: cross-reversals by Ro 15-1788 and physostigmine.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

A comparison of the central nervous system effects of haloperidol, chlorpromazine and sulpiride in normal volunteers

14 July 2018

1 reference

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Potential of moclobemide to improve cerebral insufficiency identified using a scopolamine model of aging and dementia

14 July 2018

1 reference

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TRH attenuates scopolamine-induced memory impairment in humans

14 July 2018

1 reference

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Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine

14 July 2018

1 reference

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Enhanced sensitivity to cholecystokinin tetrapeptide in panic disorder. Clinical and behavioral findings

14 July 2018

1 reference

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Models of memory dysfunction? A comparison of the effects of scopolamine and lorazepam on memory, psychomotor performance and mood

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Dose ranging study of the effects of cholecystokinin in healthy volunteers

14 July 2018

1 reference

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Effects of NMDA Modulation in Scopolamine Dementiaa

14 July 2018

1 reference

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Comparison of the effects of cholecystokinin-tetrapeptide and carbon dioxide in healthy volunteers

14 July 2018

1 reference

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Anticholinergic challenge and cognitive functions: a comparison between young and elderly normal subjects.

14 July 2018

1 reference

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Cholinesterase Inhibition in the Scopolamine Model of Dementia

14 July 2018

1 reference

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RU 41 656 does not reverse the scopolamine-induced cognitive deficit in healthy volunteers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Benzodiazepines, memory and mood: a review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Hypersensitivity to scopolamine in the elderly

14 July 2018

1 reference

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Electroencephalogram effect measures and relationships between pharmacokinetics and pharmacodynamics of centrally acting drugs

14 July 2018

1 reference

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Central Anticholinergic Hypersensitivity in Aging

14 July 2018

1 reference

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Effects of ketamine on sensory perception: evidence for a role of N-methyl-D-aspartate receptors

14 July 2018

1 reference

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Attention, learning, and personality during ketamine emergence: a pilot study

14 July 2018

1 reference

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Time-dependent changes in activity, reactivity, and responsivity during shock: Effects of cholinergic and catecholaminergic manipulations

14 July 2018

1 reference

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Effect of physostigmine and scopolamine on the memory functions of chess players

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

The effects and interactions of scopolamine, physostigmine and methamphetamine on human memory

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Studies on human memory: The interactions of diazepam, scopolamine, and physostigmine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

The use of a scopolamine model to study the potential nootropic effects of aniracetam and piracetam in healthy volunteers.

14 July 2018

1 reference

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New visions of the aging mind and brain

26 November 2018

1 reference

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Scopolamine but not lorazepam modulates face repetition priming: a psychopharmacological fMRI study

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Intravenous C-type natriuretic peptide augments behavioral and endocrine effects of cholecystokinin tetrapeptide in healthy men.

26 November 2018

1 reference

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Pharmacological modulation of behavioral and neuronal correlates of repetition priming.

26 November 2018

1 reference

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Anxiolyticlike effects of atrial natriuretic peptide on cholecystokinin tetrapeptide-induced panic attacks: preliminary findings

26 November 2018

1 reference

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Cholinergic enhancement and increased selectivity of perceptual processing during working memory

26 November 2018

1 reference

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Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia.

26 November 2018

1 reference

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Effects of low-dose cholecystokinin on respiratory function in healthy volunteers

26 November 2018

1 reference

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Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans.

26 November 2018

1 reference

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Interactive effects of subanesthetic ketamine and haloperidol in healthy humans

26 November 2018

1 reference

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Neuroanatomic correlates of CCK-4-induced panic attacks in healthy humans: a comparison of two time points

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease

26 November 2018

1 reference

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Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Fear and the brain: where have we been, and where are we going?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Scopolamine model of dementia: electroencephalogram findings and cognitive performance.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Behavioral, cardiovascular, and neuroendocrine profiles following CCK-4 challenge in healthy volunteers: a comparison of panickers and nonpanickers

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Differentiating the effects of centrally acting drugs on arousal and memory: an event-related potential study of scopolamine, lorazepam and diphenhydramine.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Glutamate modulation of dopamine measured in vivo with positron emission tomography (PET) and 11C-raclopride in normal human subjects.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine.

26 November 2018

1 reference

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The contribution of clinical pharmacology surrogates and models to drug development--a critical appraisal

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Brain mechanisms in human classical conditioning: a PET blood flow study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Anxiety sensitivity and response to cholecystokinin tetrapeptide in healthy volunteers

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Effects of the cholinomimetic SDZ ENS-163 on scopolamine-induced cognitive impairment in humans

26 November 2018

1 reference

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Scopolamine and lorazepam exert different patterns of effects in a test battery assessing stages of information processing

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Low dose intravenous infusion technique with ketamine. Amnesic, analgesic and sedative effects in human volunteers.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181700

Muscarinic and nicotinic contributions to cognitive function and cortical blood flow

26 November 2018

1 reference

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Acute and chronic role of 5-HT3 neuronal system on behavioral and neuroendocrine changes induced by intravenous cholecystokinin tetrapeptide administration in humans

26 November 2018

1 reference

12 December 2020

Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy

1 reference

12 December 2020

Functional neuroanatomy of CCK4-induced anxiety in normal healthy volunteers

1 reference

12 December 2020

Peripheral and central pharmacokinetics of apomorphine and its effect on dopamine metabolism in humans

1 reference

12 December 2020

The role of the beta-noradrenergic system in cholecystokinin-tetrapeptide-induced panic symptoms

1 reference

12 December 2020

Effects of CCK-4 infusion on the acoustic eye-blink startle and psychophysiological measures in healthy volunteers

1 reference

12 December 2020

Effects of cholecystokinin tetrapeptide on respiratory function in healthy volunteers

1 reference

12 December 2020

Effects of flumazenil on cholecystokinin-tetrapeptide-induced panic symptoms in healthy volunteers

1 reference

12 December 2020

Effects of serotonin-selective and classical antidepressants on the auditory P300 cognitive potential

1 reference

12 December 2020

Effect of aging on cholecystokinin-induced panic

1 reference

12 December 2020

Increased cognitive sensitivity to scopolamine with age and a perspective on the scopolamine model

1 reference

12 December 2020

A double-blind, placebo-controlled evaluation of the effects of orally administered venlafaxine on sleep in inpatients with major depression

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034241%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22034241

1 reference